INT265010

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Context Info
Confidence 0.20
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 1.07
Pain Relevance 1.69

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Sds) lyase activity (Sds) cellular_component (Sds)
cellular amino acid metabolic process (Sds) cytoplasm (Sds)
Anatomy Link Frequency
spinal cord 2
neurons 2
Sds (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Dorsal horn 116 100.00 Very High Very High Very High
Spinal cord 33 99.84 Very High Very High Very High
Visceral pain 4 99.36 Very High Very High Very High
Pain threshold 9 94.32 High High
electroacupuncture 43 91.72 High High
Glutamate 7 91.04 High High
nud 19 90.36 High High
Dorsal horn neuron 13 87.56 High High
spastic colon 17 87.48 High High
agonist 1 82.08 Quite High
Disease Link Frequency Relevance Heat
Nervous System Injury 92 99.72 Very High Very High Very High
Irritable Bowel Syndrome /

Irritable Bowel Syndrome Super / Visceral Pain

4 99.36 Very High Very High Very High
Pain 17 94.32 High High
Hyperalgesia 7 92.32 High High
Dyspepsia 20 90.36 High High
Stress 14 89.12 High High
Irritable Bowel Syndrome /

Irritable Bowel Syndrome Super

18 87.48 High High
Necrosis 5 50.00 Quite Low
Cancer 5 50.00 Quite Low
Neuropathic Pain 25 46.28 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
-alanine supplement in aged rats, the levels of LDH, SDH and GSH were significantly reduced, but the levels of SOD, AKP, NOS and NO had no changes.


Negative_regulation (reduced) of Gene_expression (levels) of SDH
1) Confidence 0.20 Published 2010 Journal J Biomed Sci Section Body Doc Link PMC2994374 Disease Relevance 0 Pain Relevance 0
It seems surprising that, despite facilitating spontaneous excitatory transmission (Figure 1) and decreasing the PPR of the evoked EPSCs (Figure 5) in neonatal SDH neurons after SNI, TNF?
Negative_regulation (decreasing) of Gene_expression (neurons) of SDH in neurons associated with nervous system injury and dorsal horn
2) Confidence 0.16 Published 2009 Journal Mol Pain Section Body Doc Link PMC2657778 Disease Relevance 0.32 Pain Relevance 0.55
The attenuation of visceral pain perception was associated with decreased expression of 5-HT primarily at DRN and SDH of spinal cord but not at colonic mucosa.
Negative_regulation (decreased) of Gene_expression (expression) of SDH in spinal cord associated with visceral pain, dorsal horn and spinal cord
3) Confidence 0.14 Published 2010 Journal Journal of Neurogastroenterology and Motility Section Body Doc Link PMC2912124 Disease Relevance 0.57 Pain Relevance 1.14
Two SDS molecules insert between these two opposing strands in the “10 nsec” model, thereby increasing by ?
Negative_regulation (insert) of Gene_expression (molecules) of SDS
4) Confidence 0.13 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2805716 Disease Relevance 0 Pain Relevance 0

General Comments

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