INT265015

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Context Info
Confidence 0.04
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.49
Pain Relevance 0.37

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Pgr, Sds) mitochondrion (Sds) lyase activity (Sds)
enzyme binding (Pgr) cytosol (Pgr) nucleolus (Pgr)
Anatomy Link Frequency
synapses 1
Pgr (Rattus norvegicus)
Sds (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Dorsal horn 104 100.00 Very High Very High Very High
Action potential 18 84.72 Quite High
Spinal cord 14 65.00 Quite High
Glutamate 7 62.24 Quite High
Peripheral nerve injury 16 50.00 Quite Low
Dorsal horn neuron 13 50.00 Quite Low
antagonist 1 14.84 Low Low
cytokine 17 5.00 Very Low Very Low Very Low
Neuronal excitability 7 5.00 Very Low Very Low Very Low
allodynia 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Neuropathic Pain 25 99.72 Very High Very High Very High
Nervous System Injury 92 85.04 High High
Necrosis 5 50.00 Quite Low
Cancer 5 50.00 Quite Low
Injury 7 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Nociception 2 5.00 Very Low Very Low Very Low
Hypersensitivity 2 5.00 Very Low Very Low Very Low
INFLAMMATION 2 5.00 Very Low Very Low Very Low
Hyperalgesia 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
elevates Pr at excitatory synapses within the immature SDH under neuropathic conditions, which likely contributes to the observed increase in mEPSC frequency (Figure 1).


Pr Positive_regulation (elevates) of SDH in synapses associated with neuropathic pain and dorsal horn
1) Confidence 0.04 Published 2009 Journal Mol Pain Section Body Doc Link PMC2657778 Disease Relevance 0.49 Pain Relevance 0.37

General Comments

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