INT265138

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.07
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.31

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Adrbk1) aging (Adrbk1) plasma membrane (Chrm1)
signal transducer activity (Chrm1) cytoplasm (Adrbk1)
Adrbk1 (Rattus norvegicus)
Chrm1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Kinase C 78 98.00 Very High Very High Very High
tetrodotoxin 14 80.40 Quite High
agonist 21 77.20 Quite High
Glutamate 6 5.00 Very Low Very Low Very Low
nMDA receptor 4 5.00 Very Low Very Low Very Low
Glutamate receptor 3 5.00 Very Low Very Low Very Low
imagery 3 5.00 Very Low Very Low Very Low
Action potential 2 5.00 Very Low Very Low Very Low
Hippocampus 2 5.00 Very Low Very Low Very Low
GABAergic 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Nash(non-alcoholic Steatohepatitis) 12 5.00 Very Low Very Low Very Low
Cognitive Disorder 1 5.00 Very Low Very Low Very Low
Aging 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Thus, these data are strongly suggestive that under conditions of picrotoxin-enhanced synaptic activity, GRK2 and PKCs act together to enhance M1 mACh receptor desensitization.


GRK2 Positive_regulation (enhance) of Localization (desensitization) of M1 mACh receptor
1) Confidence 0.07 Published 2007 Journal Journal of Neurochemistry Section Body Doc Link PMC2658029 Disease Relevance 0 Pain Relevance 0.31

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox