INT265224

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Context Info
Confidence 0.34
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.25
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Cd28)
Anatomy Link Frequency
T cells 2
Cd28 (Mus musculus)
IFN1@ (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 12 95.68 Very High Very High Very High
Inflammation 4 5.00 Very Low Very Low Very Low
rheumatoid arthritis 4 5.00 Very Low Very Low Very Low
abatacept 2 5.00 Very Low Very Low Very Low
Arthritis 2 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Multiple sclerosis 1 5.00 Very Low Very Low Very Low
psoriasis 1 5.00 Very Low Very Low Very Low
Crohn's disease 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Death 2 83.24 Quite High
Apoptosis 4 82.80 Quite High
Autoimmune Disease 9 5.00 Very Low Very Low Very Low
Multiple Sclerosis 7 5.00 Very Low Very Low Very Low
INFLAMMATION 4 5.00 Very Low Very Low Very Low
Diabetes Mellitus 4 5.00 Very Low Very Low Very Low
Rheumatoid Arthritis 4 5.00 Very Low Very Low Very Low
Arthritis 2 5.00 Very Low Very Low Very Low
Lyme Disease 2 5.00 Very Low Very Low Very Low
Disease 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
secretion in activated CD4+ T cells [20], we found that anti-CD28 mAb increased the proportion of IL-2-producing cells (Fig. 4A) as well as IFN-??
CD28 mAb Positive_regulation (increased) of Gene_expression (proportion) of IFN in T cells
1) Confidence 0.34 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2658739 Disease Relevance 0.25 Pain Relevance 0.05

General Comments

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