INT265265

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Context Info
Confidence 0.01
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.16
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (NAV1) cytoplasm (NAV1) transmembrane transport (SCN5A)
Anatomy Link Frequency
oocytes 2
SCN5A (Homo sapiens)
NAV1 (Homo sapiens)
SCN5A - R878C (1)
Pain Link Frequency Relevance Heat
Mexiletine 7 5.00 Very Low Very Low Very Low
lidocaine 5 5.00 Very Low Very Low Very Low
addiction 1 5.00 Very Low Very Low Very Low
tetrodotoxin 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Heart Arrhythmia 10 84.32 Quite High
Heart Rate Under Development 21 5.00 Very Low Very Low Very Low
Disease 4 5.00 Very Low Very Low Very Low
Sudden Infant Death Syndrome 2 5.00 Very Low Very Low Very Low
Syncope 1 5.00 Very Low Very Low Very Low
Premature Beats 1 5.00 Very Low Very Low Very Low
Syndrome 1 5.00 Very Low Very Low Very Low
Arrhythmias 2 Under Development 1 5.00 Very Low Very Low Very Low
Cv Unclassified Under Development 1 5.00 Very Low Very Low Very Low
Cv General 2 Under Development 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
To test for the effect of the simultaneously produced R878C-hNav1.5 mutant on the expression of WT-hNav1.5 in Xenopus oocytes, we co-injected equal amounts of the respective cRNAs into oocytes and determined the peak current amplitudes and kinetic parameters of the whole-cell Na+ currents.
R878C-hNav1.5 (R878C) Regulation (effect) of Gene_expression (expression) of hNav1 in oocytes
1) Confidence 0.01 Published 2008 Journal Acta Physiologica (Oxford, England) Section Body Doc Link PMC2659387 Disease Relevance 0.16 Pain Relevance 0

General Comments

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