INT265312

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.10
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 7
Disease Relevance 1.44
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

molecular_function (Myo1f)
Anatomy Link Frequency
muscle 2
obsolete 1
lumen 1
Myo1f (Mus musculus)
Pain Link Frequency Relevance Heat
fibrosis 1 72.80 Quite High
cytokine 11 32.88 Quite Low
corticosteroid 4 23.80 Low Low
Inflammation 28 5.00 Very Low Very Low Very Low
imagery 10 5.00 Very Low Very Low Very Low
Spinal cord 5 5.00 Very Low Very Low Very Low
Sciatic nerve 5 5.00 Very Low Very Low Very Low
Pain 5 5.00 Very Low Very Low Very Low
tolerance 3 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypertrophy 6 96.40 Very High Very High Very High
Pulmonary Disease 98 94.92 High High
Frailty 58 92.72 High High
Emphysema 1 90.72 High High
Vascular Malformations 1 89.40 High High
Bronchitis 1 89.28 High High
Telangiectasia 4 83.92 Quite High
Disease 10 81.84 Quite High
Fibrosis 1 72.80 Quite High
Muscle Weakness 6 68.92 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These fractions from both sarcomeric (Fig. 3) and soluble myosin preparations (data not shown) contained MyHCemb and MLC, indicating the presence of multimeric myosin (?
Gene_expression (preparations) of myosin
1) Confidence 0.10 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2844429 Disease Relevance 0 Pain Relevance 0
Ozz-E3 Ubiquitin Ligase Targets Sarcomeric Embryonic Myosin Heavy Chain during Muscle Development

Muscle contractile proteins are expressed as a series of developmental isoforms that are in constant dynamic remodeling during embryogenesis, but how obsolete molecules are recognized and removed is not known.

Gene_expression (expressed) of Myosin in obsolete
2) Confidence 0.09 Published 2010 Journal PLoS ONE Section Title Doc Link PMC2844429 Disease Relevance 0 Pain Relevance 0
It also is the first myosin isoform to be expressed when new myotubes form in regenerating adult muscle [21]; in intact adult muscles during hypertrophy induced by passive stretch [22]; or during recovery from immobilization-induced atrophy [23].
Gene_expression (expressed) of myosin in muscle associated with hypertrophy and frailty
3) Confidence 0.09 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2844429 Disease Relevance 0.24 Pain Relevance 0
Throughout myofibrillogenesis (E14.5-E18.5) full-length myosin eluted from the column mainly in two groups of fractions in the size ranges ?
Gene_expression (eluted) of myosin
4) Confidence 0.09 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2844429 Disease Relevance 0 Pain Relevance 0
We showed that Ozz and Elo C are present together with sarcomeric myosin from the earliest stages of myofibrillogenesis, but we saw no obvious increase in Ozz/MyHCemb ratio in association with the onset of peak periods of MyHCemb degradation during embryogenesis (e.g.
Gene_expression (present) of myosin
5) Confidence 0.09 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2844429 Disease Relevance 0 Pain Relevance 0
In addition, NO-induced contraction and relaxation of pericytes may regulate lumen size and thereby control capillary perfusion [32], functions supported by pericyte expression of the muscle isoforms of actin, myosin and tropomyosin [7].
Gene_expression (expression) of myosin in lumen
6) Confidence 0.06 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2659748 Disease Relevance 0.22 Pain Relevance 0
The loss of power in patients with COPD (Yquel et al 2006) as a result of a loss in muscle strength may be compensated for, to some extent, by the slow-to-fast transition in fiber type composition (Jobin et al 1998; Gosker, van Mameren et al 2002) and an increased proportion of hybrid fibers expressing more than one myosin heavy chain isoform (Gosker, van Mameren et al 2002).
Gene_expression (expressing) of myosin in muscle associated with pulmonary disease
7) Confidence 0.04 Published 2007 Journal International Journal of Chronic Obstructive Pulmonary Disease Section Body Doc Link PMC2695204 Disease Relevance 0.98 Pain Relevance 0.04

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox