INT265321

Context Info Confidence 0.08 First Reported 2009 Last Reported 2009 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0.17 Pain Relevance 0

Golgi apparatus (Tjp1) plasma membrane (Tjp1) nucleus (Tjp1) cytoplasm (Tjp1)

Anatomy Link Frequency Fundus 2 Tjp1 (Mus musculus)

Pain Link Frequency Relevance Heat ketamine 1 5.00 anesthesia 1 5.00 Kinase C 1 5.00 ischemia 1 5.00 isoflurane 1 5.00 Neurotransmitter 1 5.00

Disease Link Frequency Relevance Heat Apoptosis 29 84.96 Death 2 83.12 Ganglion Cysts 13 5.00 Telangiectasia 4 5.00 Pre-eclampsia 3 5.00 Retinal Diseases 2 5.00 Edema 2 5.00 Hematological Disease 2 5.00 Congenital Anomalies 2 5.00 Cancer 2 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Fundus angiography and Evans blue permeability assay revealed a breakdown of the blood-retinal-barrier that was characterized by decreased association between the tight junction proteins zo-1 and occludin.

Negative_regulation (decreased) of zo-1 Binding (association) of in Fundus

1) Confidence 0.08 Published 2009 Journal PLoS ONE Section Abstract Doc Link PMC2659748 Disease Relevance 0.17 Pain Relevance 0

General Comments

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