INT265333

Context Info Confidence 0.34 First Reported 2009 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 2 Total Number 2 Disease Relevance 0 Pain Relevance 0

cytosol (Ocln) structural molecule activity (Ocln) plasma membrane (Ocln)

Ocln (Mus musculus)

Pain Link Frequency Relevance Heat Central nervous system 3 5.00 anesthesia 2 5.00 imagery 2 5.00 ketamine 1 5.00 ischemia 1 5.00 Neurotransmitter 1 5.00 Neurobehavioral 1 5.00 Inflammatory mediators 1 5.00 metalloproteinase 1 5.00 agonist 1 5.00

Disease Link Frequency Relevance Heat Metastasis 25 50.00 Ganglion Cysts 13 43.12 Reprotox - General 3 1 21.60 Apoptosis 29 5.00 Cancer 23 5.00 Melanoma 12 5.00 Brain Tumor 6 5.00 Telangiectasia 4 5.00 Pre-eclampsia 3 5.00 Stress 3 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Immunoprecipitation of occludin followed by western blotting for zo-1 revealed that coculture of EC with 10T1/2 cells led to an increased association between occludin and zo-1 in EC, which was significantly reduced by TGF-?

Localization (Immunoprecipitation) of occludin

1) Confidence 0.34 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2659748 Disease Relevance 0 Pain Relevance 0

Therefore, we examined the effects of PCB treatment on the localization profiles of claudin-5, occludin, and ZO-1 in freshly isolated microvessels (Figures 2 and 3).

Localization (localization) of occludin

2) Confidence 0.11 Published 2010 Journal Environ Health Perspect Section Body Doc Link PMC2854723 Disease Relevance 0 Pain Relevance 0

General Comments

This test has worked.