INT265334

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Context Info
Confidence 0.17
First Reported 2009
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.96
Pain Relevance 0.20

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Smad2) intracellular (Smad2) protein complex (Smad2)
transcription factor binding (Smad2) cytoplasm (Smad2)
Smad2 (Mus musculus)
Pain Link Frequency Relevance Heat
Osteoarthritis 91 95.52 Very High Very High Very High
cytokine 5 5.00 Very Low Very Low Very Low
metalloproteinase 3 5.00 Very Low Very Low Very Low
fibrosis 2 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
ischemia 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Neurotransmitter 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Aging 13 99.68 Very High Very High Very High
Osteoarthritis 96 95.52 Very High Very High Very High
Disease 12 87.44 High High
Ganglion Cysts 13 76.12 Quite High
Adenovirus Infection 1 66.48 Quite High
Apoptosis 30 44.92 Quite Low
Hypertrophy 5 5.00 Very Low Very Low Very Low
Telangiectasia 4 5.00 Very Low Very Low Very Low
Cancer 3 5.00 Very Low Very Low Very Low
Pre-eclampsia 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
No changes in total smad2 or phosphorylation of smad1/5/8 were noted after seven days of TGF-?
Regulation (changes) of Phosphorylation (phosphorylation) of smad2
1) Confidence 0.17 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2659748 Disease Relevance 0.20 Pain Relevance 0
Expression of non phosphorylated Smad2 was not altered during ageing.
Neg (not) Regulation (altered) of Phosphorylation (phosphorylated) of Smad2 associated with aging
2) Confidence 0.14 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2875624 Disease Relevance 0.75 Pain Relevance 0.20

General Comments

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