INT265373

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Context Info
Confidence 0.17
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.10
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Hdac3) DNA binding (Hdac3) cytoplasm (Hdac3)
Hdac3 (Mus musculus)
Pain Link Frequency Relevance Heat
tolerance 2 53.12 Quite High
Eae 1 21.16 Low Low
depression 9 5.00 Very Low Very Low Very Low
antiepileptic Drug 7 5.00 Very Low Very Low Very Low
gABA 6 5.00 Very Low Very Low Very Low
Lamotrigine 6 5.00 Very Low Very Low Very Low
addiction 6 5.00 Very Low Very Low Very Low
Migraine 4 5.00 Very Low Very Low Very Low
carbamazepine 4 5.00 Very Low Very Low Very Low
aspirin 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Adhesions 1 98.88 Very High Very High Very High
Targeted Disruption 2 88.72 High High
Synovial Sarcoma 35 87.12 High High
Cancer 33 86.48 High High
Lung Cancer 1 70.20 Quite High
Leukemia 9 68.64 Quite High
Herpes Simplex Virus 1 60.24 Quite High
Sarcoma 7 58.84 Quite High
Convulsion 6 58.72 Quite High
Thyroid Neoplasm 3 58.72 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
targeting HDAC3 was obtained
Regulation (targeting) of HDAC3
1) Confidence 0.17 Published 2009 Journal Sarcoma Section Body Doc Link PMC2659882 Disease Relevance 0.56 Pain Relevance 0
HDAC3 is one of the direct targets of VPA, but until now no papers present data concerning the effect of VPA on the STAT3 pathway.

4.

Regulation (targets) of HDAC3
2) Confidence 0.08 Published 2010 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC2926634 Disease Relevance 0.54 Pain Relevance 0.03

General Comments

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