INT265383

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Context Info
Confidence 0.06
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.70
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Hsp90aa1, HDAC9) unfolded protein binding (Hsp90aa1) intracellular (Hsp90aa1)
response to stress (Hsp90aa1) cytosol (Hsp90aa1) protein folding (Hsp90aa1)
Hsp90aa1 (Mus musculus)
HDAC9 (Homo sapiens)
Pain Link Frequency Relevance Heat
Neuritis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cv General 2 Under Development 4 100.00 Very High Very High Very High
Synovial Sarcoma 35 99.08 Very High Very High Very High
Apoptosis 6 85.12 High High
Death 2 69.68 Quite High
Cancer 7 5.00 Very Low Very Low Very Low
Sarcoma 7 5.00 Very Low Very Low Very Low
Vomiting 4 5.00 Very Low Very Low Very Low
Leukemia 3 5.00 Very Low Very Low Very Low
Disease 3 5.00 Very Low Very Low Very Low
Toxicity 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Histone deacetylase (HDAC) inhibitors and the heat shock protein 90 (Hsp90) inhibitor 17-AAG have recently been shown to inhibit synovial sarcoma in preclinical models.
Hsp90 Negative_regulation (inhibitor) of HDAC associated with cv general 2 under development and synovial sarcoma
1) Confidence 0.06 Published 2009 Journal Sarcoma Section Abstract Doc Link PMC2659882 Disease Relevance 0.70 Pain Relevance 0

General Comments

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