INT265454

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Context Info
Confidence 0.17
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.16
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (TP53, CASP9) nucleus (TP53, CASP9) cell differentiation (TP53)
nucleoplasm (TP53) mitochondrion (TP53) endoplasmic reticulum (TP53)
Anatomy Link Frequency
B-cell 2
TP53 (Homo sapiens)
CASP9 (Homo sapiens)
Pain Link Frequency Relevance Heat
antagonist 1 96.00 Very High Very High Very High
Inflammation 10 50.00 Quite Low
cytokine 9 31.44 Quite Low
Pain 1 5.00 Very Low Very Low Very Low
headache 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Lymphatic System Cancer 1 98.20 Very High Very High Very High
Apoptosis 24 93.04 High High
Death 12 86.24 High High
Necrosis 2 78.92 Quite High
Cancer 2 78.56 Quite High
Stress 12 69.84 Quite High
INFLAMMATION 10 50.00 Quite Low
Disorders Of The Lacrimal System 3 5.00 Very Low Very Low Very Low
Dry Eye 2 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Indeed, phosphorylation of p53 activates the release of cytochrome c and caspase-9 via target genes such as Bax (BCL-2 [B-cell lymphoma-2] associated protein), Bak (BCL-2 homologous antagonist/killer), Noxa (damage), and PUMA (p53 upregulated modulator of apoptosis) [27].
Phosphorylation (phosphorylation) of p53 in B-cell Positive_regulation (activates) of caspase-9 associated with lymphatic system cancer, antagonist and apoptosis
1) Confidence 0.17 Published 2009 Journal Molecular Vision Section Body Doc Link PMC2660376 Disease Relevance 1.16 Pain Relevance 0.05

General Comments

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