INT265467

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Context Info
Confidence 0.01
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.84
Pain Relevance 0.29

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (HRAS, PTGS2) nucleus (HRAS, PTGS2) small molecule metabolic process (PTGS2)
endoplasmic reticulum (PTGS2) Golgi apparatus (HRAS) enzyme binding (PTGS2)
Anatomy Link Frequency
fibroblasts 2
HRAS (Homo sapiens)
PTGS2 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 9 100.00 Very High Very High Very High
Inflammation 10 92.76 High High
antagonist 1 58.96 Quite High
Pain 1 5.00 Very Low Very Low Very Low
headache 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Death 12 95.00 High High
INFLAMMATION 10 92.76 High High
Apoptosis 24 74.08 Quite High
Stress 12 69.88 Quite High
Lymphatic System Cancer 1 56.68 Quite High
Necrosis 2 30.52 Quite Low
Cancer 2 30.16 Quite Low
Disorders Of The Lacrimal System 3 5.00 Very Low Very Low Very Low
Dry Eye 2 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, Mitsui et al. recently observed that HA inhibits mRNA expression of proinflammatory cytokines and cyclooxygenase-2/prostaglandin E(2) production via CD44 in human fibroblasts [31].
HA Negative_regulation (inhibits) of Gene_expression (production) of cyclooxygenase-2 in fibroblasts associated with cytokine
1) Confidence 0.01 Published 2009 Journal Molecular Vision Section Body Doc Link PMC2660376 Disease Relevance 0.84 Pain Relevance 0.29

General Comments

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