INT265496

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Context Info
Confidence 0.25
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.89
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (CASP9) peptidase activity (CASP9) nucleus (CASP9)
intracellular (CASP9)
Anatomy Link Frequency
B-cell 2
CASP9 (Homo sapiens)
Pain Link Frequency Relevance Heat
antagonist 1 96.00 Very High Very High Very High
Inflammation 10 50.00 Quite Low
cytokine 9 31.44 Quite Low
palliative 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
psoriasis 1 5.00 Very Low Very Low Very Low
Immobilon 1 5.00 Very Low Very Low Very Low
headache 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Lymphatic System Cancer 1 98.20 Very High Very High Very High
Apoptosis 53 96.20 Very High Very High Very High
Death 21 85.32 High High
Necrosis 4 78.00 Quite High
Cancer 39 77.64 Quite High
Stress 14 69.84 Quite High
Disorder Of Lipid Metabolism 1 50.72 Quite High
Hepatocellular Cancer 20 50.00 Quite Low
INFLAMMATION 10 50.00 Quite Low
Liver Disease 1 36.52 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Indeed, phosphorylation of p53 activates the release of cytochrome c and caspase-9 via target genes such as Bax (BCL-2 [B-cell lymphoma-2] associated protein), Bak (BCL-2 homologous antagonist/killer), Noxa (damage), and PUMA (p53 upregulated modulator of apoptosis) [27].
Positive_regulation (activates) of Localization (release) of caspase-9 in B-cell associated with lymphatic system cancer, antagonist and apoptosis
1) Confidence 0.25 Published 2009 Journal Molecular Vision Section Body Doc Link PMC2660376 Disease Relevance 1.15 Pain Relevance 0.05
To support this notion, our results clearly demonstrated that the active form of caspase-9 was increased and the precursor of caspase-3 was cleaved significantly after Pa-PDT treatment (Figure 5A).
Positive_regulation (increased) of Localization (form) of caspase-9
2) Confidence 0.08 Published 2009 Journal Mol Cancer Section Body Doc Link PMC2731730 Disease Relevance 0.74 Pain Relevance 0

General Comments

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