INT265588

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Context Info
Confidence 0.47
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 5.67
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Fap) extracellular space (Fap) plasma membrane (Fap)
Fap (Mus musculus)
Pain Link Frequency Relevance Heat
Central nervous system 6 47.16 Quite Low
imagery 21 41.08 Quite Low
isoflurane 2 39.56 Quite Low
anesthesia 3 38.24 Quite Low
Inflammation 9 5.00 Very Low Very Low Very Low
Bile 8 5.00 Very Low Very Low Very Low
metalloproteinase 8 5.00 Very Low Very Low Very Low
abdominal pain 6 5.00 Very Low Very Low Very Low
cytokine 4 5.00 Very Low Very Low Very Low
COX-2 inhibitor 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Familial Adenomatous Polyposis 480 100.00 Very High Very High Very High
Familial Amyloidotic Polyneuropathy 21 100.00 Very High Very High Very High
Adenoma 116 98.26 Very High Very High Very High
Polyps 136 96.48 Very High Very High Very High
Colon Cancer 66 93.60 High High
Hereditary Nonpolyposis Colorectal Neoplasms 8 91.84 High High
Cancer 331 90.48 High High
Syndrome 18 90.40 High High
Lifespan 3 84.80 Quite High
Adenomatous Polyps 24 84.04 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In spite of the positive and exciting results obtained with this drug, doxycycline is not able to decrease all the FAP markers, and therefore we inferred that it would not perform optimally as a therapy for FAP.
Localization (decrease) of FAP associated with familial amyloidotic polyneuropathy
1) Confidence 0.47 Published 2010 Journal J Transl Med Section Body Doc Link PMC2922089 Disease Relevance 0.52 Pain Relevance 0
Genetic counseling and socio-legal aspects of FAP
Localization (aspects) of FAP associated with familial adenomatous polyposis
2) Confidence 0.45 Published 2009 Journal Orphanet J Rare Dis Section Body Doc Link PMC2772987 Disease Relevance 2.09 Pain Relevance 0
The sections were treated with the following antibodies: rabbit anti-human FSP, mouse anti-human FAP and mouse anti-human Tn-C (1?
Localization (anti) of FAP
3) Confidence 0.42 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2661372 Disease Relevance 0.46 Pain Relevance 0
Thus, it can be misdiagnosed as occurring in a patient with sporadic adenomas (Figs. 5A-C) however, it can also occur in families with members having full clinical features of FAP.
Localization (features) of FAP associated with adenoma and familial adenomatous polyposis
4) Confidence 0.40 Published 2009 Journal Orphanet J Rare Dis Section Body Doc Link PMC2772987 Disease Relevance 2.60 Pain Relevance 0

General Comments

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