INT265651

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Context Info
Confidence 0.00
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.46
Pain Relevance 0.62

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (ITGAL) cell adhesion (ITGAL) nucleus (MYCN)
plasma membrane (ITGAL) DNA binding (MYCN)
ITGAL (Homo sapiens)
MYCN (Homo sapiens)
Pain Link Frequency Relevance Heat
Glutamate 2 100.00 Very High Very High Very High
Catechol-O-methyltransferase 222 82.72 Quite High
Inflammation 16 38.64 Quite Low
Pain 44 27.44 Quite Low
intrathecal 2 25.28 Quite Low
allodynia 4 16.88 Low Low
cytokine 14 13.28 Low Low
Spinal cord 4 10.56 Low Low
IPN 12 5.00 Very Low Very Low Very Low
Central nervous system 10 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Repression 4 83.36 Quite High
Anaplastic Astrocytoma 16 66.72 Quite High
INFLAMMATION 20 38.64 Quite Low
Pain 44 27.44 Quite Low
Acquired Immune Deficiency Syndrome Or Hiv Infection 2 22.72 Low Low
Manic Depressive Disorder 2 20.84 Low Low
Schizophrenia 2 19.96 Low Low
Cancer 6 18.68 Low Low
Neuropathic Pain 8 16.88 Low Low
Inflammatory Pain 12 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
B can repress transcription by competing with steroid receptors for a common promoter cis-DNA element [59]via N-myc recruitment to the glutamate transporter gene promoter [53] and through inhibiting histone H4 acetylation at the cytochrome P-450 1A1 promoter [60].
transporter gene promoter Binding (recruitment) of N-myc associated with glutamate
1) Confidence 0.00 Published 2009 Journal Mol Pain Section Body Doc Link PMC2662804 Disease Relevance 0.23 Pain Relevance 0.31
B can repress transcription by competing with steroid receptors for a common promoter cis-DNA element [59]via N-myc recruitment to the glutamate transporter gene promoter [53] and through inhibiting histone H4 acetylation at the cytochrome P-450 1A1 promoter [60].
transporter gene promoter Binding (recruitment) of N-myc associated with glutamate
2) Confidence 0.00 Published 2009 Journal Mol Pain Section Body Doc Link PMC2662804 Disease Relevance 0.23 Pain Relevance 0.31

General Comments

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