INT265699

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Context Info
Confidence 0.15
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.49
Pain Relevance 0.14

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mRNA processing (Son) RNA binding (Son) nucleus (Son)
intracellular (Son) cell cycle (Son) DNA binding (Son)
Son (Mus musculus)
Pain Link Frequency Relevance Heat
Eae 12 80.36 Quite High
Neuropeptide 4 49.28 Quite Low
depression 36 18.16 Low Low
anesthesia 2 5.00 Very Low Very Low Very Low
amygdala 2 5.00 Very Low Very Low Very Low
neuropeptide release 2 5.00 Very Low Very Low Very Low
Hippocampus 2 5.00 Very Low Very Low Very Low
isoflurane 2 5.00 Very Low Very Low Very Low
Potency 2 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Anxiety Disorder 168 98.52 Very High Very High Very High
Depression 36 18.16 Low Low
Diabetes Insipidus 6 5.00 Very Low Very Low Very Low
Sprains And Strains 4 5.00 Very Low Very Low Very Low
Heart Rate Under Development 4 5.00 Very Low Very Low Very Low
Genetic Predisposition To Disease 4 5.00 Very Low Very Low Very Low
Hypersensitivity 4 5.00 Very Low Very Low Very Low
Agoraphobia 2 5.00 Very Low Very Low Very Low
Overdose 2 5.00 Very Low Very Low Very Low
Stress Incontinence 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Confirming microarray data, ISH revealed a decreased expression of Avp in both the PVN (Fig. 1D) and SON (Fig. 2A) in male LAB compared to both HAB and NAB mice (PVN: p<0.01 vs.
Negative_regulation (decreased) of Gene_expression (expression) of SON associated with anxiety disorder
1) Confidence 0.15 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2663030 Disease Relevance 0.77 Pain Relevance 0.08
Similarly, qPCR analysis showed a reduced Avp expression in the PVN (Fig. 1E) and SON (Fig. 2B) of both male and female LABs compared to HAB or NAB animals (PVN of male mice: p<0.05 vs.
Negative_regulation (reduced) of Gene_expression (expression) of SON associated with anxiety disorder
2) Confidence 0.13 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2663030 Disease Relevance 0.72 Pain Relevance 0.07

General Comments

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