INT265760

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.04
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 6
Disease Relevance 0.14
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (KLKB1, VEGFA) extracellular region (KLKB1, VEGFA) peptidase activity (KLKB1)
growth (VEGFA) proteinaceous extracellular matrix (VEGFA) plasma membrane (KLKB1)
Anatomy Link Frequency
plasma 6
KLKB1 (Homo sapiens)
VEGFA (Homo sapiens)
Pain Link Frequency Relevance Heat
metalloproteinase 18 7.72 Low Low
addiction 18 5.00 Very Low Very Low Very Low
antagonist 18 5.00 Very Low Very Low Very Low
ischemia 12 5.00 Very Low Very Low Very Low
Restless leg syndrome 6 5.00 Very Low Very Low Very Low
Central nervous system 6 5.00 Very Low Very Low Very Low
cytokine 6 5.00 Very Low Very Low Very Low
Inflammation 6 5.00 Very Low Very Low Very Low
tolerance 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Increased Venous Pressure Under Development 12 67.68 Quite High
Peripheral Arterial Disease 108 11.48 Low Low
Disease 42 5.00 Very Low Very Low Very Low
Coronary Artery Disease 36 5.00 Very Low Very Low Very Low
Cancer 30 5.00 Very Low Very Low Very Low
Atherosclerosis 24 5.00 Very Low Very Low Very Low
Diabetes Mellitus 24 5.00 Very Low Very Low Very Low
Eclampsia 18 5.00 Very Low Very Low Very Low
Breast Cancer 12 5.00 Very Low Very Low Very Low
Leukemia 12 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
As for the sVEGFR1-VEGF complex in plasma, its steep initial peak and dip followed those of free VEGF, while a latter steady rise was driven by the persistent net influx of free sVEGFR1.
plasma Binding (complex) of sVEGFR1-VEGF in plasma
1) Confidence 0.04 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2663039 Disease Relevance 0 Pain Relevance 0
As for the sVEGFR1-VEGF complex in plasma, its steep initial peak and dip followed those of free VEGF, while a latter steady rise was driven by the persistent net influx of free sVEGFR1.
plasma Binding (complex) of VEGF in plasma
2) Confidence 0.03 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2663039 Disease Relevance 0 Pain Relevance 0
While steady-state analyses showed that plasma concentrations of sVEGFR1 and VEGF could vary up to 164 pM and 2.4 pM respectively (>150% about controls) over the physiological range of kL, we further examined whether concentration ranges of these magnitudes were attainable within physiological time-course.

6.3.

plasma Binding (concentrations) of VEGF in plasma
3) Confidence 0.03 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2663039 Disease Relevance 0.07 Pain Relevance 0
While steady-state analyses showed that plasma concentrations of sVEGFR1 and VEGF could vary up to 164 pM and 2.4 pM respectively (>150% about controls) over the physiological range of kL, we further examined whether concentration ranges of these magnitudes were attainable within physiological time-course.

6.3.

plasma Binding (concentrations) of VEGF in plasma
4) Confidence 0.03 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2663039 Disease Relevance 0.07 Pain Relevance 0
Significant complexed fractions of VEGF and sVEGFR1 in plasma necessitate re-evaluation of assay specificity
plasma Binding (complexed) of VEGF in plasma
5) Confidence 0.03 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2663039 Disease Relevance 0 Pain Relevance 0
As for the sVEGFR1-VEGF complex in plasma, its steep initial peak and dip followed those of free VEGF, while a latter steady rise was driven by the persistent net influx of free sVEGFR1.
plasma Binding (complex) of sVEGFR1-VEGF in plasma
6) Confidence 0.03 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2663039 Disease Relevance 0 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox