INT265770

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Context Info
Confidence 0.10
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (KDR, GOPC) cytoplasm (KDR, GOPC) extracellular region (KDR)
Golgi apparatus (GOPC) cytoplasmic membrane-bounded vesicle (KDR) nucleus (KDR)
KDR (Homo sapiens)
GOPC (Homo sapiens)
Pain Link Frequency Relevance Heat
addiction 6 22.76 Low Low
metalloproteinase 6 5.00 Very Low Very Low Very Low
antagonist 6 5.00 Very Low Very Low Very Low
ischemia 4 5.00 Very Low Very Low Very Low
Restless leg syndrome 2 5.00 Very Low Very Low Very Low
Central nervous system 2 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
tolerance 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Peripheral Arterial Disease 36 5.00 Very Low Very Low Very Low
Disease 14 5.00 Very Low Very Low Very Low
Coronary Artery Disease 12 5.00 Very Low Very Low Very Low
Cancer 10 5.00 Very Low Very Low Very Low
Atherosclerosis 8 5.00 Very Low Very Low Very Low
Diabetes Mellitus 8 5.00 Very Low Very Low Very Low
Eclampsia 6 5.00 Very Low Very Low Very Low
Breast Cancer 4 5.00 Very Low Very Low Very Low
Leukemia 4 5.00 Very Low Very Low Very Low
Pressure And Volume Under Development 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The shifts in signaling profiles were as expected from the competitive binding of VEGF between VEGFRs: increasing one VEGFR's VEGF-affinity boosted formation of its signaling complexes to the detriment of the other VEGFR's complex formation (Fig. 6A).
VEGFR Binding (formation) of Fig
1) Confidence 0.10 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2663039 Disease Relevance 0 Pain Relevance 0
The minute attenuation of pro-angiogenic potential reflected a declining availability of VEGF165-bound NRP1s for coupling with VEGFR2, hence the diminishing quantities of VEGFR2-VEGF165-NRP1 (Fig. 6D).
VEGFR2 Binding (bound) of Fig
2) Confidence 0.10 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2663039 Disease Relevance 0 Pain Relevance 0

General Comments

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