INT265813

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Context Info
Confidence 0.27
First Reported 2008
Last Reported 2008
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.19
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Runx2) DNA binding (Runx2) transcription factor binding (Runx2)
cytoplasm (Runx2)
Runx2 (Mus musculus)
Pain Link Frequency Relevance Heat
Pain 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Osteoporosis 3 72.68 Quite High
Cleidocranial Dysplasia 31 62.44 Quite High
Holoprosencephaly 2 30.88 Quite Low
Congenital Anomalies 4 5.00 Very Low Very Low Very Low
Syndrome 4 5.00 Very Low Very Low Very Low
Hemorrhage 3 5.00 Very Low Very Low Very Low
Joint Instability 3 5.00 Very Low Very Low Very Low
Keloid Scars 2 5.00 Very Low Very Low Very Low
Learning Disorders 2 5.00 Very Low Very Low Very Low
Mixed Connective Tissue Disorder 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Napierala et al. 2005 reported two patients with promoter sequence variants and hypothesized that promoter mutations affecting binding of transcription factors critical for RUNX2 expression might change the transcriptional activity of the gene.
Regulation (affecting) of RUNX2 Spec (might) Binding (binding) of
1) Confidence 0.27 Published 2008 Journal American Journal of Medical Genetics. Part a Section Body Doc Link PMC2663417 Disease Relevance 0.19 Pain Relevance 0

General Comments

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