INT26606

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Context Info
Confidence 0.65
First Reported 1980
Last Reported 2010
Negated 2
Speculated 0
Reported most in Body
Documents 19
Total Number 19
Disease Relevance 7.18
Pain Relevance 1.46

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (RNASE1)
Anatomy Link Frequency
pancreas 2
proximal 1
pituitary 1
brain 1
rib 1
RNASE1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Chronic pancreatitis 14 94.80 High High
Angina 1 78.68 Quite High
antagonist 17 77.20 Quite High
Enkephalin 6 61.36 Quite High
Dynorphin 2 56.60 Quite High
Neurotransmitter 2 55.80 Quite High
Opioid 2 55.12 Quite High
Inflammation 43 45.12 Quite Low
cytokine 14 5.00 Very Low Very Low Very Low
Pain 12 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Mycobacterial Infection 10 99.96 Very High Very High Very High
Cancer 142 99.68 Very High Very High Very High
Pancreatic Cancer 21 98.48 Very High Very High Very High
Breast Cancer 15 98.24 Very High Very High Very High
Obstructive Jaundice 8 96.60 Very High Very High Very High
Pancreatitis 20 94.84 High High
Nicotine Addiction 30 92.04 High High
Disease 34 88.68 High High
Jaundice 5 87.52 High High
Apoptosis 85 87.28 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Our recommendation for detecting rib TB is an accurate medical history and physical examination, and early differential diagnosis with bone scintigram, computed tomogram, and percutaneous needle biopsy.
Gene_expression (detecting) of rib in rib associated with mycobacterial infection
1) Confidence 0.65 Published 1999 Journal Respirology Section Abstract Doc Link 10489667 Disease Relevance 0.92 Pain Relevance 0.08
In contrast, serum RNase rose in only 8 percent of patients with other cancers, 11 percent of other patients with obstructive jaundice and in no patients with chronic pancreatitis.
Neg (no) Gene_expression (rose) of serum RNase associated with cancer, chronic pancreatitis and obstructive jaundice
2) Confidence 0.64 Published 1980 Journal Am. J. Surg. Section Abstract Doc Link 7350842 Disease Relevance 1.08 Pain Relevance 0.25
The serum levels of a poly-[C]-specific acid ribonuclease (RNase) found in the pancreas was measured in 40 normal persons and 137 patients with pancreatic cancer, other cancers, obstructive jaundice, acute pancreatitis or chronic pancreatitis.
Gene_expression (found) of RNase in pancreas associated with cancer, pancreatitis, pancreatic cancer, chronic pancreatitis and obstructive jaundice
3) Confidence 0.57 Published 1980 Journal Am. J. Surg. Section Abstract Doc Link 7350842 Disease Relevance 0.87 Pain Relevance 0.15
Analysis of the serum isoenzymes of RNase by isoelectric focusing did not reveal any unique RNases produced by the tumours.
Neg (not) Gene_expression (produced) of RNase associated with cancer
4) Confidence 0.57 Published 1980 Journal Am. J. Surg. Section Abstract Doc Link 7350842 Disease Relevance 1.08 Pain Relevance 0.25
The serum levels of a poly-[C]-specific acid ribonuclease (RNase) found in the pancreas was measured in 40 normal persons and 137 patients with pancreatic cancer, other cancers, obstructive jaundice, acute pancreatitis or chronic pancreatitis.
Gene_expression (found) of ribonuclease in pancreas associated with cancer, pancreatitis, pancreatic cancer, chronic pancreatitis and obstructive jaundice
5) Confidence 0.50 Published 1980 Journal Am. J. Surg. Section Abstract Doc Link 7350842 Disease Relevance 0.87 Pain Relevance 0.15
Significant correlations were detected among AGL, GGT and RNase.
Gene_expression (detected) of RNase
6) Confidence 0.32 Published 1989 Journal Nephron Section Abstract Doc Link 2563574 Disease Relevance 0.99 Pain Relevance 0.16
We used RNase protection mapping to assess the abundance in the brain and pituitary of preproenkephalin transcripts that initiate within intron A.
Gene_expression (protection) of RNase in brain
7) Confidence 0.28 Published 2004 Journal Brain Res. Bull. Section Abstract Doc Link 15130700 Disease Relevance 0 Pain Relevance 0.17
RNA transcripts for in vitro polyadenylation, in vivo polyadenylation assays and RNase protection assays were synthesized by use of SP6 or T7 RNA polymerase according to the supplier (Promega) in the presence of 50 ?
Gene_expression (synthesized) of RNase
8) Confidence 0.22 Published 2005 Journal Nucleic Acids Research Section Body Doc Link PMC1088970 Disease Relevance 0 Pain Relevance 0
Total RNA isolation and RNase protection assay
Gene_expression (assay) of RNase
9) Confidence 0.19 Published 2005 Journal Nucleic Acids Research Section Body Doc Link PMC1088970 Disease Relevance 0 Pain Relevance 0
To determine polyadenylation signal use in vivo, total RNA from transfected cells was assayed by RNase protection.
Gene_expression (protection) of RNase
10) Confidence 0.19 Published 2005 Journal Nucleic Acids Research Section Body Doc Link PMC1088970 Disease Relevance 0 Pain Relevance 0
RNase protection assays will produce a protected fragment of 168 bases if the COX-2 proximal polyadenylation signal is used; utilization of the BGH signal will produce a protected fragment of 410 bases.
Gene_expression (produce) of RNase in proximal
11) Confidence 0.19 Published 2005 Journal Nucleic Acids Research Section Body Doc Link PMC1088970 Disease Relevance 0.09 Pain Relevance 0
For RNase protection assay reactions, 5 ?
Gene_expression (protection) of RNase
12) Confidence 0.19 Published 2005 Journal Nucleic Acids Research Section Body Doc Link PMC1088970 Disease Relevance 0 Pain Relevance 0
Total RNA was isolated after 24 h, RNase protection assays were performed using the antisense probe to the pC?
Gene_expression (protection) of RNase
13) Confidence 0.19 Published 2005 Journal Nucleic Acids Research Section Body Doc Link PMC1088970 Disease Relevance 0.10 Pain Relevance 0
In Figure 1, we demonstrate that filtration, DNAse and RNAse treatment increases the efficiency of amplification of Adenovirus Type 17 DNA, whereas this combined treatment eliminates amplification of genomic ?
Gene_expression (filtration) of RNAse
14) Confidence 0.17 Published 2007 Journal Virol J Section Body Doc Link PMC1950496 Disease Relevance 0 Pain Relevance 0
in PBS containing DNase-free RNase (type II-A) and propidium
Gene_expression (free) of RNase
15) Confidence 0.14 Published 2007 Journal PPAR Research Section Body Doc Link PMC1852897 Disease Relevance 0.17 Pain Relevance 0.04
in PBS containing DNase-free RNase (type II-A) and propidium
Gene_expression (propidium) of RNase
16) Confidence 0.14 Published 2007 Journal PPAR Research Section Body Doc Link PMC1852897 Disease Relevance 0.17 Pain Relevance 0.04
We used RNase protection mapping to assess the abundance in the brain and pituitary of preproenkephalin transcripts that initiate within intron A.
Gene_expression (protection) of RNase in pituitary
17) Confidence 0.10 Published 2004 Journal Brain Res. Bull. Section Abstract Doc Link 15130700 Disease Relevance 0 Pain Relevance 0.17
It is possible that one or more components of CS can attack the structure of the IRE1 transmembrane protein thereby disabling its ribonuclease function and subsequent splicing of the XBP1 mRNA to its transcriptionally active isoform.
Gene_expression (function) of ribonuclease
18) Confidence 0.08 Published 2008 Journal BMC Cancer Section Body Doc Link PMC2527015 Disease Relevance 0.70 Pain Relevance 0
Using a method of RNase protection assays to map the 3?
Gene_expression (protection) of RNase
19) Confidence 0.04 Published 2010 Journal Veterinary Research Section Body Doc Link PMC2896810 Disease Relevance 0.14 Pain Relevance 0

General Comments

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