INT266103

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Context Info
Confidence 0.04
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.78
Pain Relevance 0.21

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (SNRNP70) mitochondrion (COMT) small molecule metabolic process (COMT)
cytoplasm (COMT) cytosol (COMT) mRNA processing (SNRNP70)
Anatomy Link Frequency
red blood cells 1
COMT (Homo sapiens)
SNRNP70 (Homo sapiens)
Pain Link Frequency Relevance Heat
Catechol-O-methyltransferase 109 100.00 Very High Very High Very High
Inflammation 1 58.40 Quite High
Catecholamine 7 56.36 Quite High
Glutamate 1 28.24 Quite Low
Pain 19 5.00 Very Low Very Low Very Low
Dopamine 3 5.00 Very Low Very Low Very Low
Fibrositis 2 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
Lasting pain 1 5.00 Very Low Very Low Very Low
Morphine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Schizophrenia 5 100.00 Very High Very High Very High
Aggression 1 100.00 Very High Very High Very High
Hantavirus Infection 78 88.96 High High
Temporomandibular Joint Disorders 5 71.56 Quite High
Hyperhomocysteinemia 2 62.08 Quite High
Nutritional Deficiencies 1 60.48 Quite High
Injury 1 58.88 Quite High
INFLAMMATION 1 58.40 Quite High
Stress 2 57.84 Quite High
Cancer 2 16.96 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This minor SNP, producing an alanine to serine substitution at codon 72, has been associated with aggressive behavior and schizophrenia risk as well as with COMT activity in red blood cells collected from study participants [32], [33].
COMT Binding (associated) of SNP in red blood cells associated with catechol-o-methyltransferase, aggression and schizophrenia
1) Confidence 0.04 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2664927 Disease Relevance 0.78 Pain Relevance 0.21

General Comments

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