INT266126

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Context Info
Confidence 0.30
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.84
Pain Relevance 0.27

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (SH2B2) signal transduction (SH2B2) plasma membrane (SH2B2)
cytoplasm (SH2B2) signal transducer activity (SH2B2)
SH2B2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Glutamate 1 98.16 Very High Very High Very High
Catechol-O-methyltransferase 109 90.72 High High
Catecholamine 7 53.36 Quite High
Inflammation 1 49.12 Quite Low
Pain 19 10.36 Low Low
Dopamine 3 5.00 Very Low Very Low Very Low
Fibrositis 2 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
Lasting pain 1 5.00 Very Low Very Low Very Low
Morphine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hantavirus Infection 78 99.80 Very High Very High Very High
Cancer 2 85.04 High High
Cardiovascular Disease 2 84.16 Quite High
Schizophrenia 5 83.68 Quite High
Neurodegenerative Disease 2 83.20 Quite High
Hyperhomocysteinemia 2 78.04 Quite High
Stress 2 49.76 Quite Low
INFLAMMATION 1 49.12 Quite Low
Injury 1 47.68 Quite Low
Nutritional Deficiencies 1 45.92 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Functional polymorphisms in genes relevant to homocysteine metabolism (e.g., 5,10-methylenetetrahydrofolate reductase; MTHFR and glutamate carboxypepidase II; GCPII [59]–[61]) that result in accumulation of SAH likely augment the effects of APS and HPS haplotypes.
Regulation (effects) of APS associated with glutamate and hantavirus infection
1) Confidence 0.30 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2664927 Disease Relevance 0.84 Pain Relevance 0.27

General Comments

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