INT266254

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Context Info
Confidence 0.31
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 0.43
Pain Relevance 0.76

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Lhb) molecular_function (Lhb) cellular_component (Lhb)
biological_process (Lhb)
Anatomy Link Frequency
tendon 1
ependymal cells 1
locus coeruleus 1
Lhb (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Locus ceruleus 4 93.72 High High
imagery 10 92.08 High High
midbrain 14 91.36 High High
IPN 43 81.28 Quite High
tetrodotoxin 6 78.80 Quite High
Nucleus accumbens 7 77.48 Quite High
Action potential 12 72.08 Quite High
Substantia nigra 5 71.00 Quite High
GABAergic 7 64.92 Quite High
Raphe 21 61.96 Quite High
Disease Link Frequency Relevance Heat
Increased Venous Pressure Under Development 1 99.84 Very High Very High Very High
Rotator Cuff Tears 49 75.84 Quite High
Injury 3 66.88 Quite High
Rupture 1 58.40 Quite High
Arthropathy 9 42.96 Quite Low
Dislocations 2 29.08 Quite Low
Targeted Disruption 5 7.32 Low Low
Handedness 14 5.00 Very Low Very Low Very Low
Depression 11 5.00 Very Low Very Low Very Low
Cognitive Disorder 11 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Rathbun and Macnab suggested a vascular insufficiency in the affected area of the LHB at the entrance to the biceps groove to be responsible for the degeneration of the tendon [23].
Regulation (affected) of LHB in tendon associated with increased venous pressure under development
1) Confidence 0.31 Published 2010 Journal BMC Musculoskelet Disord Section Body Doc Link PMC2936349 Disease Relevance 0.43 Pain Relevance 0
Other efferent targets of the LHb include several thalamic nuclei (centromedial, mediodorsal, ventromedial, parafascicular nucleus), the superior colliculus, the dorsal tegmental region and locus coeruleus (Herkenham & Nauta 1979).



Regulation (targets) of LHb in locus coeruleus associated with locus ceruleus
2) Confidence 0.22 Published 2008 Journal Philosophical Transactions of the Royal Society B: Biological Sciences Section Body Doc Link PMC2666075 Disease Relevance 0 Pain Relevance 0.47
Acquired images were transferred to ImageJ (version 1.37a, NIH, USA) and a region of interest tool was used to delineate discrete areas (MHb, LHb, ependymal cells of the third ventricle, and single cells) and assess relative bioluminescence over time.
Regulation (ependymal cells) of LHb in ependymal cells
3) Confidence 0.21 Published 2010 Journal Neuroscience Section Body Doc Link PMC2928449 Disease Relevance 0 Pain Relevance 0.29
Circadian oscillations of PER2::LUC bioluminescence were observed in the LHb in 10 cultures and in the ependymal layer in 8.
Regulation (oscillations) of LHb
4) Confidence 0.18 Published 2010 Journal Neuroscience Section Body Doc Link PMC2928449 Disease Relevance 0 Pain Relevance 0

General Comments

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