INT266331

Context Info Confidence 0.30 First Reported 2009 Last Reported 2009 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 11 Disease Relevance 0.76 Pain Relevance 0

nucleus (S100a1) cytoplasm (S100a1)

Anatomy Link Frequency liver 1 muscle 1 brain 1 spleen 1 thymus 1 S100a1 (Mus musculus)

Pain Link Frequency Relevance Heat imagery 11 45.28 Inflammation 605 5.00 Abeta 132 5.00 cytokine 121 5.00 fibrosis 44 5.00 Osteoarthritis 22 5.00 Inflammatory response 22 5.00 metalloproteinase 22 5.00 Arthritis 22 5.00 endometriosis 11 5.00

Disease Link Frequency Relevance Heat Apoptosis 154 68.96 Cancer 341 50.00 INFLAMMATION 638 5.00 Stress 143 5.00 Diabetes Mellitus 132 5.00 Adhesions 88 5.00 Lung Cancer 77 5.00 Disease 77 5.00 Death 66 5.00 Injury 66 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

S100A1 normally exists as a homodimer, and its mRNA is observed most prominently in the heart, with decreasing levels in kidney, liver, skin, brain, lung, stomach, testis, muscle, small intestine, thymus and spleen.

Transcription (observed) of S100A1 in skin

1) Confidence 0.30 Published 2009 Journal J Transl Med Section Body Doc Link PMC2666642 Disease Relevance 0.07 Pain Relevance 0

S100A1 normally exists as a homodimer, and its mRNA is observed most prominently in the heart, with decreasing levels in kidney, liver, skin, brain, lung, stomach, testis, muscle, small intestine, thymus and spleen.

Transcription (observed) of S100A1 in stomach

2) Confidence 0.10 Published 2009 Journal J Transl Med Section Body Doc Link PMC2666642 Disease Relevance 0.07 Pain Relevance 0

S100A1 normally exists as a homodimer, and its mRNA is observed most prominently in the heart, with decreasing levels in kidney, liver, skin, brain, lung, stomach, testis, muscle, small intestine, thymus and spleen.

Transcription (observed) of S100A1 in small intestine

3) Confidence 0.10 Published 2009 Journal J Transl Med Section Body Doc Link PMC2666642 Disease Relevance 0.07 Pain Relevance 0

S100A1 normally exists as a homodimer, and its mRNA is observed most prominently in the heart, with decreasing levels in kidney, liver, skin, brain, lung, stomach, testis, muscle, small intestine, thymus and spleen.

Transcription (observed) of S100A1 in thymus

4) Confidence 0.10 Published 2009 Journal J Transl Med Section Body Doc Link PMC2666642 Disease Relevance 0.07 Pain Relevance 0

S100A1 normally exists as a homodimer, and its mRNA is observed most prominently in the heart, with decreasing levels in kidney, liver, skin, brain, lung, stomach, testis, muscle, small intestine, thymus and spleen.

Transcription (observed) of S100A1 in spleen

5) Confidence 0.10 Published 2009 Journal J Transl Med Section Body Doc Link PMC2666642 Disease Relevance 0.07 Pain Relevance 0

S100A1 normally exists as a homodimer, and its mRNA is observed most prominently in the heart, with decreasing levels in kidney, liver, skin, brain, lung, stomach, testis, muscle, small intestine, thymus and spleen.

Transcription (observed) of S100A1 in brain

6) Confidence 0.10 Published 2009 Journal J Transl Med Section Body Doc Link PMC2666642 Disease Relevance 0.07 Pain Relevance 0

S100A1 normally exists as a homodimer, and its mRNA is observed most prominently in the heart, with decreasing levels in kidney, liver, skin, brain, lung, stomach, testis, muscle, small intestine, thymus and spleen.

Transcription (observed) of S100A1 in liver

7) Confidence 0.10 Published 2009 Journal J Transl Med Section Body Doc Link PMC2666642 Disease Relevance 0.07 Pain Relevance 0

S100A1 normally exists as a homodimer, and its mRNA is observed most prominently in the heart, with decreasing levels in kidney, liver, skin, brain, lung, stomach, testis, muscle, small intestine, thymus and spleen.

Transcription (observed) of S100A1 in lung

8) Confidence 0.10 Published 2009 Journal J Transl Med Section Body Doc Link PMC2666642 Disease Relevance 0.07 Pain Relevance 0

S100A1 normally exists as a homodimer, and its mRNA is observed most prominently in the heart, with decreasing levels in kidney, liver, skin, brain, lung, stomach, testis, muscle, small intestine, thymus and spleen.

Transcription (observed) of S100A1 in kidney

9) Confidence 0.10 Published 2009 Journal J Transl Med Section Body Doc Link PMC2666642 Disease Relevance 0.07 Pain Relevance 0

S100A1 normally exists as a homodimer, and its mRNA is observed most prominently in the heart, with decreasing levels in kidney, liver, skin, brain, lung, stomach, testis, muscle, small intestine, thymus and spleen.

Transcription (observed) of S100A1 in muscle

10) Confidence 0.10 Published 2009 Journal J Transl Med Section Body Doc Link PMC2666642 Disease Relevance 0.07 Pain Relevance 0

S100A1 normally exists as a homodimer, and its mRNA is observed most prominently in the heart, with decreasing levels in kidney, liver, skin, brain, lung, stomach, testis, muscle, small intestine, thymus and spleen.

Transcription (observed) of S100A1 in testis

11) Confidence 0.10 Published 2009 Journal J Transl Med Section Body Doc Link PMC2666642 Disease Relevance 0.07 Pain Relevance 0

General Comments

This test has worked.