INT266373

Context Info Confidence 0.01 First Reported 2009 Last Reported 2009 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.84 Pain Relevance 0.10

extracellular space (Ager) cell adhesion (Itgam) plasma membrane (Ager) nucleus (Itgam) cytoplasm (Ager)

Itgam (Mus musculus) Ager (Mus musculus)

Pain Link Frequency Relevance Heat Inflammation 55 83.08 Inflammatory stimuli 1 68.72 Inflammatory marker 1 44.32 Inflammatory response 2 27.96 cytokine 11 21.16 Abeta 12 5.00 fibrosis 4 5.00 Osteoarthritis 2 5.00 metalloproteinase 2 5.00 Arthritis 2 5.00

Disease Link Frequency Relevance Heat Charcot Marie Tooth Disease 2 95.20 Adhesions 8 92.64 Diabetes Mellitus 12 86.40 INFLAMMATION 58 83.08 Disease 7 80.80 Stress 13 71.68 Cancer 31 50.00 Albuminuria 1 48.76 Renal Disease 1 39.44 Motor Neuron Diseases 1 35.24

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

For example, HMGB1, S100B, Mac-1, and S100A6 activate RAGE through distinct signal transduction pathways [42,43].

Mac-1 Positive_regulation (activate) of RAGE

1) Confidence 0.01 Published 2009 Journal J Transl Med Section Body Doc Link PMC2666642 Disease Relevance 0.84 Pain Relevance 0.10

General Comments

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