INT266376

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Context Info
Confidence 0.00
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 2.31
Pain Relevance 0.54

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Ager) cell adhesion (Itgam) nucleus (Itgam)
plasma membrane (Ager) cytoplasm (Ager)
Ager (Mus musculus)
Itgam (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 165 100.00 Very High Very High Very High
Inflammatory response 6 98.48 Very High Very High Very High
cytokine 33 20.88 Low Low
metalloproteinase 6 19.52 Low Low
Abeta 36 5.00 Very Low Very Low Very Low
fibrosis 12 5.00 Very Low Very Low Very Low
Osteoarthritis 6 5.00 Very Low Very Low Very Low
Arthritis 6 5.00 Very Low Very Low Very Low
endometriosis 3 5.00 Very Low Very Low Very Low
Inflammatory marker 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 174 100.00 Very High Very High Very High
Adhesions 24 96.60 Very High Very High Very High
Lung Cancer 21 90.80 High High
Esophageal Cancer 3 58.76 Quite High
Cancer 93 55.72 Quite High
Metastasis 9 55.32 Quite High
Apoptosis 42 54.72 Quite High
Glioma 9 48.96 Quite Low
Disease 21 47.60 Quite Low
Diabetes Mellitus 36 42.24 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
HMGB1 enhances RAGE-Mac1 interactions on inflammatory cells, linking it to inflammatory responses (Table 4) [71,72].
RAGE Binding (interactions) of Mac1 associated with inflammatory response and inflammation
1) Confidence 0.00 Published 2009 Journal J Transl Med Section Body Doc Link PMC2666642 Disease Relevance 0.91 Pain Relevance 0.16
HMGB1 enhances RAGE-Mac1 interactions on inflammatory cells, linking it to inflammatory responses (Table 4) [71,72].
RAGE Binding (interactions) of Mac1 associated with inflammatory response and inflammation
2) Confidence 0.00 Published 2009 Journal J Transl Med Section Body Doc Link PMC2666642 Disease Relevance 0.91 Pain Relevance 0.16
However soluble RAGE has functions other than just blocking fl-RAGE function, and exerts pro-inflammatory properties through interaction with Mac-1 [10,29].
RAGE Binding (interaction) of Mac-1 associated with inflammation
3) Confidence 0.00 Published 2009 Journal J Transl Med Section Body Doc Link PMC2666642 Disease Relevance 0.49 Pain Relevance 0.22

General Comments

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