INT266379

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Context Info
Confidence 0.01
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.30
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (S100a8, Ager) plasma membrane (S100a8, Ager) cytoplasm (S100a8, Ager)
extracellular region (S100a8) cytoskeleton (S100a8)
S100a8 (Mus musculus)
Ager (Mus musculus)
Pain Link Frequency Relevance Heat
imagery 1 89.48 High High
Inflammation 55 39.28 Quite Low
Abeta 12 5.00 Very Low Very Low Very Low
cytokine 11 5.00 Very Low Very Low Very Low
fibrosis 4 5.00 Very Low Very Low Very Low
Osteoarthritis 2 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
metalloproteinase 2 5.00 Very Low Very Low Very Low
Arthritis 2 5.00 Very Low Very Low Very Low
endometriosis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 14 88.64 High High
Targeted Disruption 4 74.64 Quite High
Colon Cancer 1 57.84 Quite High
Cancer 31 50.00 Quite Low
INFLAMMATION 58 39.28 Quite Low
Stress 13 5.00 Very Low Very Low Very Low
Diabetes Mellitus 12 5.00 Very Low Very Low Very Low
Adhesions 8 5.00 Very Low Very Low Very Low
Lung Cancer 7 5.00 Very Low Very Low Very Low
Disease 7 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
S100A8 and S100A9 have not been directly shown to activate RAGE, but there is substantial functional evidence that many of their effects are blocked by RAGE suppression or silencing.
S100A8 Positive_regulation (activate) of RAGE
1) Confidence 0.01 Published 2009 Journal J Transl Med Section Body Doc Link PMC2666642 Disease Relevance 0.30 Pain Relevance 0.04

General Comments

This test has worked.

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