INT266381

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Context Info
Confidence 0.00
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.77
Pain Relevance 0.55

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Ager, Nfkb1) mitochondrion (Nfkb1) DNA binding (Nfkb1)
protein complex (Nfkb1) cytosol (Nfkb1) extracellular space (Ager)
Anatomy Link Frequency
neurons 2
Ager (Mus musculus)
Nfkb1 (Mus musculus)
Pain Link Frequency Relevance Heat
Abeta 12 99.98 Very High Very High Very High
cINOD 1 54.48 Quite High
Inflammation 55 53.92 Quite High
cytokine 11 5.00 Very Low Very Low Very Low
fibrosis 4 5.00 Very Low Very Low Very Low
Osteoarthritis 2 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
metalloproteinase 2 5.00 Very Low Very Low Very Low
Arthritis 2 5.00 Very Low Very Low Very Low
endometriosis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 13 100.00 Very High Very High Very High
Amyloid Plaque 1 90.64 High High
Toxicity 1 88.96 High High
Alzheimer's Dementia 2 86.24 High High
Drug Induced Neurotoxicity 1 73.84 Quite High
Neuroblastoma 1 69.28 Quite High
Death 6 63.44 Quite High
INFLAMMATION 58 53.92 Quite High
Cancer 31 50.00 Quite Low
Drug Hypersensitivity 1 45.88 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
On neurons, Abeta activation of RAGE will generate oxidative stress and activate NF-KB.
Positive_regulation (activation) of RAGE in neurons Positive_regulation (activate) of NF-KB associated with stress and abeta
1) Confidence 0.00 Published 2009 Journal J Transl Med Section Body Doc Link PMC2666642 Disease Relevance 0.77 Pain Relevance 0.55

General Comments

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