INT266389

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Context Info
Confidence 0.04
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.50
Pain Relevance 0.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (S100a6) nuclear envelope (S100a6) peptidase activity (C2)
extracellular region (C2) plasma membrane (S100a6) nucleus (S100a6)
C2 (Mus musculus)
S100a6 (Mus musculus)
Pain Link Frequency Relevance Heat
Osteoarthritis 2 71.84 Quite High
metalloproteinase 2 70.96 Quite High
Inflammation 55 11.64 Low Low
Abeta 12 5.00 Very Low Very Low Very Low
cytokine 11 5.00 Very Low Very Low Very Low
fibrosis 4 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
Arthritis 2 5.00 Very Low Very Low Very Low
endometriosis 1 5.00 Very Low Very Low Very Low
Inflammatory marker 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Breast Cancer 2 97.40 Very High Very High Very High
Injury 6 79.76 Quite High
Apoptosis 14 79.28 Quite High
Osteoarthritis 2 71.84 Quite High
Cancer 31 64.00 Quite High
Disease 7 47.04 Quite Low
Noninfiltrating Intraductal Carcinoma 1 32.40 Quite Low
INFLAMMATION 58 11.64 Low Low
Bacterial Respiratory Disease 1 6.64 Low Low
Stress 13 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
S100A6 bound significantly to the C2 domain of RAGE, as opposed to the V and/or C1 domains to which most other ligands bind and thus suggests that it might have a discordant function from other RAGE ligands.
C2 Binding (bound) of S100A6
1) Confidence 0.04 Published 2009 Journal J Transl Med Section Body Doc Link PMC2666642 Disease Relevance 0.50 Pain Relevance 0.07

General Comments

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