INT266418

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Context Info
Confidence 0.09
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.37
Pain Relevance 0.23

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (HMGB1, Tlr4) nucleoplasm (HMGB1) intracellular (Tlr4)
DNA binding (HMGB1) signal transduction (Tlr4) extracellular space (HMGB1)
HMGB1 (Homo sapiens)
Tlr4 (Mus musculus)
Pain Link Frequency Relevance Heat
Cytokine 11 99.28 Very High Very High Very High
inflammation 55 95.44 Very High Very High Very High
abeta 12 5.00 Very Low Very Low Very Low
fibrosis 4 5.00 Very Low Very Low Very Low
Osteoarthritis 2 5.00 Very Low Very Low Very Low
inflammatory response 2 5.00 Very Low Very Low Very Low
Metalloproteinase 2 5.00 Very Low Very Low Very Low
Arthritis 2 5.00 Very Low Very Low Very Low
endometriosis 1 5.00 Very Low Very Low Very Low
inflammatory marker 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 58 95.44 Very High Very High Very High
Stress 13 88.68 High High
Cancer 31 50.00 Quite Low
Adhesions 8 43.48 Quite Low
Apoptosis 14 33.08 Quite Low
Hepatocellular Cancer 1 7.76 Low Low
Cirrhosis 1 5.52 Low Low
Diabetes Mellitus 12 5.00 Very Low Very Low Very Low
Lung Cancer 7 5.00 Very Low Very Low Very Low
Disease 7 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
HMGB1 binds LPS and a variety of cytokines such as IL-1?.
HMGB1 Binding (binds) of LPS associated with cytokine
1) Confidence 0.09 Published 2009 Journal J Transl Med Section Body Doc Link PMC2666642 Disease Relevance 0.37 Pain Relevance 0.23

General Comments

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