INT266423

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Context Info
Confidence 0.04
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.90
Pain Relevance 0.20

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (HMGB1, Mapk3) cytoplasm (HMGB1, Mapk3) nucleus (HMGB1, Mapk3)
protein complex assembly (Mapk3) DNA binding (HMGB1) protein complex (Mapk3)
HMGB1 (Homo sapiens)
Mapk3 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 55 99.92 Very High Very High Very High
cytokine 11 84.16 Quite High
Abeta 12 5.00 Very Low Very Low Very Low
fibrosis 4 5.00 Very Low Very Low Very Low
Osteoarthritis 2 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
metalloproteinase 2 5.00 Very Low Very Low Very Low
Arthritis 2 5.00 Very Low Very Low Very Low
endometriosis 1 5.00 Very Low Very Low Very Low
Inflammatory marker 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 58 99.92 Very High Very High Very High
Apoptosis 14 95.80 Very High Very High Very High
Adhesions 8 93.20 High High
Cancer 31 86.08 High High
Hepatocellular Cancer 1 70.48 Quite High
Cirrhosis 1 68.24 Quite High
Stress 13 5.00 Very Low Very Low Very Low
Diabetes Mellitus 12 5.00 Very Low Very Low Very Low
Lung Cancer 7 5.00 Very Low Very Low Very Low
Disease 7 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
HMGB1 signaling, in part through RAGE, is associated with ERK1, ERK2, Jun-NH2-kinase (JNK), and p38 signaling.
HMGB1 Binding (associated) of ERK1
1) Confidence 0.04 Published 2009 Journal J Transl Med Section Body Doc Link PMC2666642 Disease Relevance 0.90 Pain Relevance 0.20

General Comments

This test has worked.

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