INT266660

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Context Info
Confidence 0.06
First Reported 2009
Last Reported 2009
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.08
Pain Relevance 0.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (MMP9) extracellular space (MMP9) extracellular region (MMP9)
proteinaceous extracellular matrix (MMP9) plasma membrane (PTGER2) extracellular matrix organization (MMP9)
PTGER2 (Homo sapiens)
MMP9 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 2 78.44 Quite High
Inflammation 15 78.04 Quite High
COX2 1 76.64 Quite High
metalloproteinase 3 50.00 Quite Low
Angina 2 5.00 Very Low Very Low Very Low
Inflammatory mediators 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 17 78.04 Quite High
Rupture 4 5.00 Very Low Very Low Very Low
Atherosclerotic Plaque 3 5.00 Very Low Very Low Very Low
Cv General 3 Under Development 2 5.00 Very Low Very Low Very Low
Atherosclerosis 2 5.00 Very Low Very Low Very Low
Death 1 5.00 Very Low Very Low Very Low
Metabolic Disorder 1 5.00 Very Low Very Low Very Low
Cardiovascular Disease 1 5.00 Very Low Very Low Very Low
Stroke 1 5.00 Very Low Very Low Very Low
Leukemia 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Also, it has been shown that PGE2 alone does not stimulate MMP-9 synthesis in MonoMac 6 cells but needs a simultaneous presence of an effective primary stimulus such as TNF?
PGE2 Neg (not) Positive_regulation (stimulate) of Gene_expression (synthesis) of MMP-9
1) Confidence 0.06 Published 2009 Journal Lipids Health Dis Section Body Doc Link PMC2667508 Disease Relevance 0.08 Pain Relevance 0.12

General Comments

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