INT266703

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Context Info
Confidence 0.26
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.10
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (RYR1, DIXDC1) cytosol (DIXDC1) intracellular (DIXDC1)
plasma membrane (RYR1) cell cycle (DIXDC1) signal transducer activity (DIXDC1)
RYR1 (Homo sapiens)
DIXDC1 (Homo sapiens)
RYR1 - G4898R (1)
Pain Link Frequency Relevance Heat
addiction 2 28.64 Quite Low
potassium channel 2 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Central Core Disease 12 100.00 Very High Very High Very High
Disease 3 5.00 Very Low Very Low Very Low
Hypothermia 1 5.00 Very Low Very Low Very Low
Malignant Hyperthermia 1 5.00 Very Low Very Low Very Low
Neuromuscular Disease 1 5.00 Very Low Very Low Very Low
Malignant Neoplastic Disease 1 5.00 Very Low Very Low Very Low
Muscular Dystrophy 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We compare in Figure 2 the ion permeation properties of wild type RyR1-WT [5] with RyR1-D4899Q [5] and CCD associated RyR1-G4898R [28] mutant channels.
RyR1-G4898R (G4898R) Binding (associated) of CCD associated with central core disease
1) Confidence 0.26 Published 2009 Journal PLoS Computational Biology Section Body Doc Link PMC2668181 Disease Relevance 0.10 Pain Relevance 0

General Comments

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