INT26676

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Context Info
Confidence 0.14
First Reported 1987
Last Reported 1989
Negated 1
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 0
Pain Relevance 1.73

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Pomc, Trh) extracellular region (Pomc, Trh) cell-cell signaling (Pomc)
extracellular space (Pomc) generation of precursor metabolites and energy (Pomc) signal transduction (Pomc)
Anatomy Link Frequency
stomach 4
Pomc (Rattus norvegicus)
Trh (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Endogenous opioid 10 100.00 Very High Very High Very High
Enkephalin 4 100.00 Very High Very High Very High
Dynorphin 2 100.00 Very High Very High Very High
Opioid 4 91.72 High High
Neurotransmitter 1 89.20 High High
narcan 6 69.20 Quite High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The effect of endogenous opioid peptides (beta-endorphin, leucine-enkephalin, dynorphin 1-13 on the release of thyrotropin releasing hormone (TRH) from the rat stomach in vitro was studied.
beta-endorphin Regulation (effect) of Localization (release) of thyrotropin releasing hormone in stomach associated with dynorphin, endogenous opioid and enkephalin
1) Confidence 0.14 Published 1989 Journal Endocrinol. Exp. Section Abstract Doc Link 2565806 Disease Relevance 0 Pain Relevance 0.58
The effect of endogenous opioid peptides (beta-endorphin, leucine-enkephalin, dynorphin 1-13 on the release of thyrotropin releasing hormone (TRH) from the rat stomach in vitro was studied.
beta-endorphin Regulation (effect) of Localization (release) of TRH in stomach associated with dynorphin, endogenous opioid and enkephalin
2) Confidence 0.14 Published 1989 Journal Endocrinol. Exp. Section Abstract Doc Link 2565806 Disease Relevance 0 Pain Relevance 0.58
Both met-enkephalin and beta-endorphin stimulated the release of VIP significantly whilst not affecting the release of TRH.
beta-endorphin Neg (not) Regulation (affecting) of Localization (release) of TRH associated with enkephalin
3) Confidence 0.10 Published 1987 Journal Life Sci. Section Abstract Doc Link 3102870 Disease Relevance 0 Pain Relevance 0.57

General Comments

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