INT266788

Context Info Confidence 0.05 First Reported 2007 Last Reported 2007 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 1.07 Pain Relevance 0.53

cytosol (FBXW11) nucleus (FBXW11) cell cycle (FBXW11) cytoplasm (FBXW11)

FBXW11 (Homo sapiens)

Pain Link Frequency Relevance Heat Inflammation 44 96.04 endometriosis 168 85.12 cytokine 27 78.36 substance P 21 5.00 Nerve growth factor 16 5.00 Pain 16 5.00 metalloproteinase 13 5.00 Catecholamine 8 5.00 pain pelvic 5 5.00 Dismenorea 4 5.00

Disease Link Frequency Relevance Heat Stress 34 96.28 INFLAMMATION 44 96.04 Disease 24 86.80 Endometriosis 224 85.12 Hypersensitivity 1 76.64 Adhesions 13 32.24 Reprotox - General 3 21 5.00 Pain 17 5.00 Choristoma 5 5.00 Apoptosis 5 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

HOs are required to degrade heme into biliverdin and carbon monoxide (CO) to avoid toxic heme effects such as oxidative stress; hence, HOs have been proposed to be involved in tissue protection.

Protein_catabolism (degrade) of HOs associated with stress

1) Confidence 0.05 Published 2007 Journal Semin Immunopathol Section Body Doc Link PMC2668599 Disease Relevance 1.07 Pain Relevance 0.53

General Comments

This test has worked.