INT266813

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Context Info
Confidence 0.03
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.78
Pain Relevance 0.14

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (CNNM3)
Anatomy Link Frequency
pancreas 1
CNNM3 (Homo sapiens)
Pain Link Frequency Relevance Heat
antidepressant 74 87.00 High High
iatrogenic 1 76.88 Quite High
depression 6 38.20 Quite Low
fluoxetine 5 37.36 Quite Low
Nortriptyline 4 36.32 Quite Low
Serotonin 6 8.40 Low Low
Endep 2 5.00 Very Low Very Low Very Low
agonist 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Diabetes Mellitus 27 97.44 Very High Very High Very High
Xerostomia 1 92.48 High High
Insulin Resistance 2 84.24 Quite High
Weight Gain 2 82.92 Quite High
Hypoglycemia 43 82.88 Quite High
Body Weight 1 53.36 Quite High
Depression 7 38.20 Quite Low
Appetite Loss 2 34.80 Quite Low
Hyperinsulinism 1 32.48 Quite Low
Obesity 1 28.36 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In addition, peripheral blockade of M3 receptors in beta cells results in suppression of insulin secretion and raised leptin levels (also inhibiting insulin secretion by the pancreas), thereby increasing the risk of hyperglycaemia [5, 26].
Negative_regulation (blockade) of M3 in pancreas
1) Confidence 0.03 Published 2008 Journal Eur J Clin Pharmacol Section Body Doc Link PMC2668653 Disease Relevance 0.78 Pain Relevance 0.14

General Comments

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