INT266824

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Context Info
Confidence 0.27
First Reported 2008
Last Reported 2008
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.22
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Fgf23) extracellular space (Fgf23) extracellular region (Fgf23)
Fgf23 (Mus musculus)
Pain Link Frequency Relevance Heat
Pain 1 22.56 Low Low
Somatostatin 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypophosphatemia 11 98.84 Very High Very High Very High
Disease 10 98.46 Very High Very High Very High
Rickets 73 86.16 High High
Bone Cancer 1 79.04 Quite High
Familial Hypophosphatemia 3 62.36 Quite High
Hypercalcemia 3 57.28 Quite High
Congenital Anomalies 3 28.72 Quite Low
Muscle Weakness 2 24.56 Low Low
Pain 1 22.56 Low Low
Cancer 12 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, in the short-term, the new discoveries underline the evidence that current forms of treatment with calcitriol and phosphate supplements only partially address some of the defects in the disease (hypophosphataemia and low to normal 1,25(OH)2D concentrations), but do not alter the disturbed underlying mechanisms, such as elevated FGF23 and MEPE levels and the peri-osteocytic mineralisation defects.
Neg (not) Regulation (alter) of Positive_regulation (elevated) of FGF23 associated with hypophosphatemia and disease
1) Confidence 0.27 Published 2008 Journal Eur J Pediatr Section Body Doc Link PMC2668657 Disease Relevance 1.22 Pain Relevance 0

General Comments

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