INT266927

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Context Info
Confidence 0.46
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 2.50
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (ERBB2) signal transduction (ERBB2) plasma membrane (ERBB2)
nucleus (ERBB2) cytoplasm (ERBB2)
ERBB2 (Homo sapiens)
Pain Link Frequency Relevance Heat
cva 2 68.08 Quite High
headache 3 5.00 Very Low Very Low Very Low
palliative 1 5.00 Very Low Very Low Very Low
pruritus 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Adenocarcinoma 6 99.84 Very High Very High Very High
Skin Cancer 6 99.48 Very High Very High Very High
Noninfiltrating Intraductal Carcinoma 3 99.48 Very High Very High Very High
Cancer 37 99.32 Very High Very High Very High
Carcinoma 3 97.08 Very High Very High Very High
Ductal Carcinoma 1 96.44 Very High Very High Very High
Carcinoma In Situ 6 91.80 High High
Advanced Or Metastatic Breast Cancer 19 88.56 High High
Breast Cancer 61 86.92 High High
Disease 9 84.08 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The levels of HER-2 mRNA were significantly higher in ADC than SCC tumor samples (median values of 0.38 (interquartile range 0.24–0.51) a.u. versus 0.10 (0.07–0.13) a.u., P < .001), whereas the difference was not significant for the EGFR transcript (Figure 1(a)).
Positive_regulation (higher) of Transcription (levels) of HER-2 associated with adenocarcinoma, cancer and skin cancer
1) Confidence 0.46 Published 2010 Journal Journal of Nucleic Acids Section Body Doc Link PMC2911612 Disease Relevance 0.86 Pain Relevance 0.03
Furthermore, DCIS frequently overexpresses mutated p53, HER-2/neu,
Positive_regulation (mutated) of Transcription (neu) of HER-2 associated with noninfiltrating intraductal carcinoma
2) Confidence 0.42 Published 2009 Journal Journal of Oncology Section Body Doc Link PMC2668926 Disease Relevance 1.64 Pain Relevance 0

General Comments

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