INT26701

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Context Info
Confidence 0.05
First Reported 1989
Last Reported 1989
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.56
Pain Relevance 0.69

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
vas deferens 1
Tic1 (Mus musculus)
Pain Link Frequency Relevance Heat
agonist 3 98.84 Very High Very High Very High
antagonist 4 94.04 High High
antinociception 2 88.44 High High
Antinociceptive 1 86.88 High High
Potency 1 82.08 Quite High
Opioid 1 75.00 Quite High
mu opioid receptor 1 63.52 Quite High
Somatostatin 1 60.84 Quite High
Enkephalin 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Tics 7 100.00 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The compounds demonstrated varying degrees of intrinsic agonist activity especially in the mouse vas deferens, the least active being CTAP and D-Tic-CTAP, which showed no mu or kappa agonist actions, and delta activity only at very high (greater than 3 microM) concentrations.
Positive_regulation (active) of D-Tic-CTAP in vas deferens associated with tics and agonist
1) Confidence 0.05 Published 1989 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 2566679 Disease Relevance 0.56 Pain Relevance 0.69

General Comments

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