INT267123

Context Info Confidence 0.01 First Reported 2007 Last Reported 2007 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 1.05 Pain Relevance 0.31

cell differentiation (ROS1) mitochondrion (Nfkb1) DNA binding (Nfkb1) protein complex (Nfkb1) cytoplasm (Nfkb1) cell proliferation (ROS1)

ROS1 (Homo sapiens) Nfkb1 (Mus musculus)

Pain Link Frequency Relevance Heat COX2 53 100.00 cINOD 4 5.00 cOX1 2 5.00 cytokine 1 5.00 Inflammation 1 5.00 alcohol 1 5.00

Disease Link Frequency Relevance Heat Stress 3 99.28 Conjunctiva Disease 44 89.12 Disease 2 82.08 Cancer 8 80.68 Apoptosis 3 5.00 Retinoblastoma 2 5.00 Skin Cancer 2 5.00 INFLAMMATION 2 5.00 Colon Cancer 2 5.00 Burns 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Moreover, ROS can induce cyclooxygenase 2 (COX 2) formation via activation of the NF-kB signaling pathway [8].

ROS Positive_regulation (induce) of Positive_regulation (activation) of NF-kB associated with cox2

1) Confidence 0.01 Published 2007 Journal Molecular Vision Section Body Doc Link PMC2669508 Disease Relevance 1.05 Pain Relevance 0.31

General Comments

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