INT267158

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Context Info
Confidence 0.02
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.46
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (IRS1) mitochondrion (SHMT2) signal transduction (IRS1)
methyltransferase activity (SHMT2) plasma membrane (IRS1) nucleus (IRS1)
IRS1 (Homo sapiens)
SHMT2 (Homo sapiens)
Pain Link Frequency Relevance Heat
tolerance 5 95.68 Very High Very High Very High
cytokine 3 5.00 Very Low Very Low Very Low
Alcohol 3 5.00 Very Low Very Low Very Low
agonist 2 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
inflammatory 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Diabetes Mellitus 45 98.80 Very High Very High Very High
Impaired Glucose Tolerance 5 95.68 Very High Very High Very High
Obesity 52 76.88 Quite High
Insulin Resistance 7 73.36 Quite High
Hyperinsulinism 3 37.40 Quite Low
Alzheimer's Dementia 13 5.00 Very Low Very Low Very Low
Polycystic Ovary Syndrome 12 5.00 Very Low Very Low Very Low
Hypertension 6 5.00 Very Low Very Low Very Low
Cancer 6 5.00 Very Low Very Low Very Low
Disorder Of Lipid Metabolism 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Similarly, the Gly > Arg mutation (Gly97Arg) of the insulin receptor substrate 1 (IRS1) is associated with a 15% increased risk of type 2 diabetes, although the difference is not significant [110].
substrate 1 Binding (associated) of Gly associated with diabetes mellitus
1) Confidence 0.02 Published 2009 Journal PPAR Research Section Body Doc Link PMC2669649 Disease Relevance 0.46 Pain Relevance 0.05

General Comments

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