INT267251

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Context Info
Confidence 0.12
First Reported 2009
Last Reported 2009
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 4
Disease Relevance 2.02
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

phosphatase activity (Ptprj) plasma membrane (Ptprj)
Ptprj (Mus musculus)
Pain Link Frequency Relevance Heat
imagery 4 54.92 Quite High
Paracetamol 4 5.00 Very Low Very Low Very Low
aspirin 4 5.00 Very Low Very Low Very Low
Central nervous system 4 5.00 Very Low Very Low Very Low
Antinociceptive 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 148 99.64 Very High Very High Very High
Death 120 96.08 Very High Very High Very High
Leukemia 12 94.64 High High
Cancer 52 89.28 High High
Colon Cancer 4 88.72 High High
Toxicity 16 84.48 Quite High
Skin Cancer 8 83.04 Quite High
Neuroblastoma 4 71.28 Quite High
Targeted Disruption 32 40.84 Quite Low
Lung Cancer 8 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
BE is easily isolated and therefore plays an important role as raw material for the production of BetA and other biologically active compounds [7].
Gene_expression (production) of BetA
1) Confidence 0.12 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2671171 Disease Relevance 0.62 Pain Relevance 0
Cholesterol strongly enhances cytotoxic effects of BE but not BetA
Neg (not) Gene_expression (not) of BetA
2) Confidence 0.11 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2671171 Disease Relevance 0.39 Pain Relevance 0.03
Cholesterol strongly enhances cytotoxic effects of BE but not BetA
Gene_expression (effects) of BetA
3) Confidence 0.11 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2671171 Disease Relevance 0.39 Pain Relevance 0.03
We previously showed that Bcl-2 over-expression delayed BetA-induced apoptosis[17], but curiously in the case of BE/cholesterol it has very limited effect on the amount of cytotoxicity induced (Figure 4).
Gene_expression (expression) of BetA associated with apoptosis
4) Confidence 0.11 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2671171 Disease Relevance 0.62 Pain Relevance 0

General Comments

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