INT267256

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Context Info
Confidence 0.11
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.14
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (FAS, Fadd) signal transduction (FAS, Fadd) aging (FAS)
protein complex assembly (FAS) protein complex (Fadd) signal transducer activity (FAS)
Anatomy Link Frequency
plasma 2
FAS (Homo sapiens)
Fadd (Mus musculus)
Pain Link Frequency Relevance Heat
Paracetamol 2 5.00 Very Low Very Low Very Low
aspirin 2 5.00 Very Low Very Low Very Low
Central nervous system 2 5.00 Very Low Very Low Very Low
Antinociceptive 2 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 74 98.54 Very High Very High Very High
Death 60 82.68 Quite High
Cancer 26 50.00 Quite Low
Lung Cancer 4 47.12 Quite Low
Toxicity 8 35.12 Quite Low
Reprotox - General 1 2 23.84 Low Low
Targeted Disruption 16 5.00 Very Low Very Low Very Low
Leukemia 6 5.00 Very Low Very Low Very Low
Skin Cancer 4 5.00 Very Low Very Low Very Low
Neuroblastoma 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In addition, cholesterol-enriched micro-domains, so called lipid rafts, are important signal transduction platforms [24], which have been related to apoptosis [25] and changes in plasma cholesterol levels have been associated with Fas-FADD complex formation and caspase-8 activation [26], [27].
Fas Binding (formation) of FADD in plasma associated with apoptosis
1) Confidence 0.11 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2671171 Disease Relevance 0.57 Pain Relevance 0
In addition, cholesterol-enriched micro-domains, so called lipid rafts, are important signal transduction platforms [24], which have been related to apoptosis [25] and changes in plasma cholesterol levels have been associated with Fas-FADD complex formation and caspase-8 activation [26], [27].
Fas Binding (formation) of FADD in plasma associated with apoptosis
2) Confidence 0.11 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2671171 Disease Relevance 0.57 Pain Relevance 0

General Comments

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