INT267587

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Context Info
Confidence 0.00
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 2.04
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (PTAFR, PTPRC) nucleolus (PTAFR) nucleus (PTAFR)
signal transducer activity (PTAFR)
Anatomy Link Frequency
eustachian tube 3
cavity 3
PTAFR (Homo sapiens)
PTPRC (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 333 71.76 Quite High
bradykinin 18 56.08 Quite High
cytokine 189 49.80 Quite Low
Inflammatory mediators 72 5.00 Very Low Very Low Very Low
chemokine 51 5.00 Very Low Very Low Very Low
Inflammatory response 33 5.00 Very Low Very Low Very Low
metalloproteinase 15 5.00 Very Low Very Low Very Low
fibrosis 6 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
potassium channel 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Otitis Media 402 99.92 Very High Very High Very High
Otitis Media With Effusion 276 92.68 High High
Adhesions 42 88.72 High High
Hyperplasia 12 81.88 Quite High
Metaplasia 12 81.40 Quite High
INFLAMMATION 432 71.76 Quite High
Disease 6 70.72 Quite High
Suppurative Otitis Media 12 68.72 Quite High
Edema 30 14.68 Low Low
Cholesteatoma 144 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
By stimulating mucous glycoprotein release, PAF appears to be a mediator in the hypersecretion of mucus in the middle ear cavity and eustachian tube (141).
PAF Positive_regulation (stimulating) of Localization (release) of glycoprotein in cavity
1) Confidence 0.00 Published 2008 Journal Clinical and Experimental Otorhinolaryngology Section Body Doc Link PMC2671742 Disease Relevance 0.53 Pain Relevance 0.03
PAF also stimulates secretion of mucus glycoprotein mediated by arachidonic acid metabolites, especially metabolites of the lipoxygenase pathway via a PAF-receptor dependent mechanism (244), and inhibits mucociliary clearance of the eustachian tube (245).
PAF Positive_regulation (stimulates) of Localization (secretion) of glycoprotein in eustachian tube
2) Confidence 0.00 Published 2008 Journal Clinical and Experimental Otorhinolaryngology Section Body Doc Link PMC2671742 Disease Relevance 0.98 Pain Relevance 0.04
By stimulating mucous glycoprotein release, PAF appears to be a mediator in the hypersecretion of mucus in the middle ear cavity and eustachian tube (141).
PAF Positive_regulation (stimulating) of in eustachian tube Localization (release) of glycoprotein in cavity
3) Confidence 0.00 Published 2008 Journal Clinical and Experimental Otorhinolaryngology Section Body Doc Link PMC2671742 Disease Relevance 0.53 Pain Relevance 0.03

General Comments

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