INT267588

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Context Info
Confidence 0.01
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 2.25
Pain Relevance 1.11

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (IL10, IL6) extracellular region (IL10, IL6) aging (IL6)
intracellular (IL10) cell-cell signaling (IL10) response to stress (IL10)
Anatomy Link Frequency
macrophages 3
monocytes 1
IL10 (Homo sapiens)
IL6 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 222 100.00 Very High Very High Very High
cytokine 126 100.00 Very High Very High Very High
Inflammatory mediators 48 5.00 Very Low Very Low Very Low
chemokine 34 5.00 Very Low Very Low Very Low
Inflammatory response 22 5.00 Very Low Very Low Very Low
bradykinin 12 5.00 Very Low Very Low Very Low
metalloproteinase 10 5.00 Very Low Very Low Very Low
fibrosis 4 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
potassium channel 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 288 100.00 Very High Very High Very High
Infection 28 92.48 High High
Otitis Media With Effusion 184 87.68 High High
Otitis Media 268 85.84 High High
Cholesteatoma 96 5.00 Very Low Very Low Very Low
Adhesions 28 5.00 Very Low Very Low Very Low
Edema 20 5.00 Very Low Very Low Very Low
Hypersensitivity 18 5.00 Very Low Very Low Very Low
Metaplasia 8 5.00 Very Low Very Low Very Low
Rhinitis 8 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
IL-10, being the key anti-inflammatory cytokine, inhibits monocytes/macrophages and the production of TNF, IL-1, IL-6 and IL-8 (84).
IL-10 Negative_regulation (inhibits) of Gene_expression (production) of IL-6 in macrophages associated with inflammation and cytokine
1) Confidence 0.01 Published 2008 Journal Clinical and Experimental Otorhinolaryngology Section Body Doc Link PMC2671742 Disease Relevance 1.12 Pain Relevance 0.55
IL-10, being the key anti-inflammatory cytokine, inhibits monocytes/macrophages and the production of TNF, IL-1, IL-6 and IL-8 (84).
IL-10 Negative_regulation (inhibits) of in monocytes Gene_expression (production) of IL-6 in macrophages associated with inflammation and cytokine
2) Confidence 0.00 Published 2008 Journal Clinical and Experimental Otorhinolaryngology Section Body Doc Link PMC2671742 Disease Relevance 1.12 Pain Relevance 0.55

General Comments

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