INT267593

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Context Info
Confidence 0.00
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.06
Pain Relevance 0.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (IL8, MUC1) signal transduction (IL8) extracellular space (IL8)
plasma membrane (MUC1) nucleus (MUC1) intracellular (IL8)
Anatomy Link Frequency
goblet cells 2
IL8 (Homo sapiens)
MUC1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 111 73.28 Quite High
Inflammatory response 11 40.08 Quite Low
cytokine 63 25.04 Quite Low
chemokine 17 8.60 Low Low
rheumatoid arthritis 1 5.76 Low Low
Inflammatory mediators 24 5.00 Very Low Very Low Very Low
bradykinin 6 5.00 Very Low Very Low Very Low
metalloproteinase 5 5.00 Very Low Very Low Very Low
fibrosis 2 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Otitis Media 134 97.56 Very High Very High Very High
Otitis Media With Effusion 92 95.20 Very High Very High Very High
Recurrence 3 91.68 High High
INFLAMMATION 144 73.28 Quite High
Adhesions 14 36.40 Quite Low
Disease 2 12.16 Low Low
Increased Venous Pressure Under Development 4 7.12 Low Low
Rheumatoid Arthritis 1 5.76 Low Low
Cholesteatoma 48 5.00 Very Low Very Low Very Low
Infection 14 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
and that IL-8 stimulates prolonged mucin secretion from goblet cells and may be involved in the maintenance of OM in the the chronic stage.
IL-8 Positive_regulation (stimulates) of Localization (secretion) of mucin in goblet cells associated with otitis media
1) Confidence 0.00 Published 2008 Journal Clinical and Experimental Otorhinolaryngology Section Body Doc Link PMC2671742 Disease Relevance 1.06 Pain Relevance 0.06

General Comments

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