INT267606

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Context Info
Confidence 0.48
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.39
Pain Relevance 0.43

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (CCL5) aging (CCL5) extracellular region (CCL5)
cell-cell signaling (CCL5) cytoplasm (CCL5)
Anatomy Link Frequency
stromal cell 1
CCL5 (Homo sapiens)
Pain Link Frequency Relevance Heat
chemokine 19 100.00 Very High Very High Very High
Inflammation 125 86.24 High High
Multiple sclerosis 1 54.16 Quite High
rheumatoid arthritis 4 53.20 Quite High
Inflammatory response 11 36.08 Quite Low
cytokine 65 26.80 Quite Low
Neurotransmitter 2 16.28 Low Low
Inflammatory mediators 24 5.00 Very Low Very Low Very Low
bradykinin 10 5.00 Very Low Very Low Very Low
Neuropeptide 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Otitis Media 134 87.72 High High
INFLAMMATION 156 86.24 High High
Otitis Media With Effusion 92 78.84 Quite High
Disease 4 72.28 Quite High
Asthma 23 72.24 Quite High
Chronic Sinusitis 2 70.52 Quite High
Rhinitis 16 65.12 Quite High
Viral Infection 1 61.12 Quite High
Hypersensitivity 17 60.72 Quite High
Demyelinating Disease 1 54.16 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
DPP IV degrades interferon (IFN) gamma - induced chemokines, CCL3, CCL5 (RANTES), CCL11, CCL22, and CXCL12 (stromal cell-derived factor-1 alpha; SDF-1?).
Protein_catabolism (degrades) of CCL5 in stromal cell associated with chemokine
1) Confidence 0.48 Published 2010 Journal Allergy Asthma Clin Immunol Section Body Doc Link PMC2877018 Disease Relevance 0.44 Pain Relevance 0.16
The concentration of RANTES was positively correlated with the endotoxin content (114).
Protein_catabolism (concentration) of RANTES
2) Confidence 0.04 Published 2008 Journal Clinical and Experimental Otorhinolaryngology Section Body Doc Link PMC2671742 Disease Relevance 0.95 Pain Relevance 0.27

General Comments

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