INT267610

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Context Info
Confidence 0.03
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.08
Pain Relevance 0.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (MAPK14) nucleoplasm (MAPK14) signal transduction (MAPK14)
nucleus (MAPK14) response to stress (MAPK14) cytoplasm (MAPK14)
MAPK14 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 63 90.24 High High
Inflammation 111 77.88 Quite High
Inflammatory mediators 24 5.00 Very Low Very Low Very Low
chemokine 17 5.00 Very Low Very Low Very Low
Inflammatory response 11 5.00 Very Low Very Low Very Low
bradykinin 6 5.00 Very Low Very Low Very Low
metalloproteinase 5 5.00 Very Low Very Low Very Low
fibrosis 2 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
potassium channel 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cholesteatoma 48 89.20 High High
Otitis Media 134 79.40 Quite High
INFLAMMATION 144 77.88 Quite High
Otitis Media With Effusion 92 74.52 Quite High
Disease 2 63.04 Quite High
Adhesions 14 59.36 Quite High
Bacterial Infection 4 30.48 Quite Low
Hyperplasia 4 27.96 Quite Low
Metaplasia 4 27.48 Quite Low
Infection 14 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
-Smad signaling, however, led to down-regulation of p38 by including MAPK phosphatase-1 (MKP-1), thereby acting as a negative regulator for MUC5AC induction (248).


Negative_regulation (down) of Negative_regulation (regulation) of p38
1) Confidence 0.03 Published 2008 Journal Clinical and Experimental Otorhinolaryngology Section Body Doc Link PMC2671742 Disease Relevance 1.08 Pain Relevance 0.15

General Comments

This test has worked.

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