INT267796

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Context Info
Confidence 0.61
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 0.77
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Capns1) cytoplasm (Capns1)
Capns1 (Mus musculus)
Pain Link Frequency Relevance Heat
imagery 1 29.68 Quite Low
alcohol 10 5.00 Very Low Very Low Very Low
cINOD 8 5.00 Very Low Very Low Very Low
depression 4 5.00 Very Low Very Low Very Low
anesthesia 4 5.00 Very Low Very Low Very Low
ketamine 3 5.00 Very Low Very Low Very Low
Central nervous system 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stomach Cancer 4 79.68 Quite High
Lissencephaly 4 62.16 Quite High
Muscular Dystrophy 8 61.48 Quite High
Death 4 59.44 Quite High
Apoptosis 4 53.32 Quite High
Disease 8 32.80 Quite Low
Injury 26 5.00 Very Low Very Low Very Low
Targeted Disruption 14 5.00 Very Low Very Low Very Low
Stress 12 5.00 Very Low Very Low Very Low
Ulcers 10 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Although calpains 8 and 9 share this domain structure with calpains 1 and 2, when expressed alone in cultured cells or E. coli, calpain 8 is active without CAPNS1 and forms a homo-oligomer [11], whereas calpain 9 requires the co-expression of CAPNS1 [12].
Gene_expression (expression) of CAPNS1
1) Confidence 0.61 Published 2010 Journal PLoS Genetics Section Body Doc Link PMC2912385 Disease Relevance 0.38 Pain Relevance 0
Although calpains 8 and 9 share this domain structure with calpains 1 and 2, when expressed alone in cultured cells or E. coli, calpain 8 is active without CAPNS1 and forms a homo-oligomer [11], whereas calpain 9 requires the co-expression of CAPNS1 [12].
Gene_expression (expression) of CAPNS1
2) Confidence 0.61 Published 2010 Journal PLoS Genetics Section Body Doc Link PMC2912385 Disease Relevance 0.39 Pain Relevance 0
SSs and CSs were considered isolated from a single PC if the CS caused a statistically significant 8?
Gene_expression (considered) of CSs
3) Confidence 0.00 Published 2008 Journal Frontiers in Systems Neuroscience Section Body Doc Link PMC2671936 Disease Relevance 0 Pain Relevance 0

General Comments

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